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Nutrition · Chris Masterjohn, PhD

Mastering Nutrition

by Chris Masterjohn, PhD

Welcome to the Mastering Nutrition podcast. Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks. He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign's College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.

Latest episodes

Showing 20 · updated from the feed

Depression Starts In Your Mitochondria

You could be one metabolic bottleneck away from feeling amazing. Mitome is the first at-home test that measures your cellular energy directly and gives you a personaliz

Dec 15 2025
6 min

Aging is best explained by declining mitochondrial function over time.

  Aging is best explained by declining mitochondrial function over time.   This answers its own "why."   Mitochondria produce the energy needed for repair so if any of it

Dec 9 2025
3 min

The Medical Myth That Nutritional Deficiencies Are A Thing of the Past

This is a clip from Joe Rogan Experience JRE 2420.  Watch the full interview here: https://www.youtube.com/watch?v=QBn54YNnKD0 Chris Masterjohn, PhD, is the Founder

Dec 7 2025
1 min

Why Doctors Think They Can Ignore the Studies Suggesting Seed Oils Cause Heart Disease

This is a clip from Joe Rogan Experience JRE 2420. Watch the full interview here: https://www.youtube.com/watch?v=QBn54YNnKD0

Dec 7 2025
2 min

The Problem With Seed Oils and Why They Are So Controversial

This is a clip from Joe Rogan Experience Episode 2420. You can watch the full interview here: https://www.youtube.com/watch?v=QBn54YNnKD0

Dec 5 2025
5 min

Mitochondria: Why They Control Everything in Human Health

Mitochondria govern everything. Watch this with the slides here: https://www.youtube.com/watch?v=mED1_L3wZbc Mitochondria convert your food to usable energy in the

Dec 4 2025
1 h 42 min

SSRI Withdrawal Is Mitochondrial Dysfunction

Chris Masterjohn, PhD, Founder and Scientific Director of mito.me, explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medica

Nov 23 2025
1 h 29 min

How Lactate Alkalinizes Your Muscles

For a long time, most people believed that when we exercise, our muscles make lactic acid, this acidifies the muscles, and the acidity contributes to contractile failure,

Sep 6 2024
1 h 34 min

D-Lactate: Groundbreaking Research No One Is Talking About

D-lactate is commonly stated to be exclusively a microbial metabolite.  This is found in assumptions within the medical literature for decades even when it was long-kno

Jul 31 2024
1 h 30 min

Handling Creatine Side Effects

In this podcast we cover elevated creatinine, insomnia, cramps constipation, water retention, hair loss, irritation and anger, lightheadedness during lifting, bloating, a

Jul 12 2024
2 min

Your Cells Are Starving For Creatine

Creatine is like your second mitochondria. Or, the mitochondria's chief of staff. Or its co-pilot. Your mitochondria make ATP so you can see clearly, hear accurately, d

Jul 12 2024
28 min

Is Whole Food Vitamin C Really Different? | Masterjohn Q&A Files #330

Question: Is whole food vitamin C superior to natural because it is part of a tyrosinase complex? Short Answer: Vitamin C is nearly ubiquitously distributed in plant ti

Dec 18 2023
23 min

What's the Deal With Seed Oils? | Masterjohn Q&A Files #329

Question: What Is the Real Issue With Seed Oils? Short Answer: The main issue with seed oils is that they present an oxidative liability. They do not acutely cause oxi

Dec 4 2023
30 min

Is Hair Mineral Testing Useful? | Masterjohn Q&A Files #328

Question: How useful is hair trace mineral analysis (HTMA) for nutritional testing? Short Answer: Hair trace mineral analysis is included as an optional add-on in the c

Nov 20 2023
24 min

Secrets to Superior Cognitive Performance (Without Drugs)

Nutrition is far more powerful than drugs to improve cognitive performance. We start by looking at cocaine, Adderall, and Ritalin, and show why these drugs cannot possi

Nov 17 2023
51 min

Vitamin C, Whole Food Vs. Synthetic: Does It Matter?

Debunking the myth that vitamin C in plants is found in a special "tyrosinase complex." For the written article with references, see here: https://chrismasterjohnphd.su

Nov 16 2023
7 min

Fact-Checking Gary Brecka on Rogan: A Deep Dive into MTHFR and Methylation

Watch or listen to the full critique here: https://www.youtube.com/watch?v=kMPvCiOkEtQ Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondr

Nov 14 2023
6 min

Cancer, IV Drips, and the Glutathione Vitamin C Connection

Is high-dose vitamin C good for you?   High-dose intravenous vitamin C can selectively kill cancer cells in live patients and can save sepsis patients from dying, but

Nov 6 2023
2 min

How to Find the Root Cause of Autoimmunity? | Masterjohn Q&A Files #327

Question: How to Find the Root Cause of Autoimmunity? Short Answer: Autoimmune conditions are likely driven by deficiencies of vitamins A and D, which contribute to po

Nov 6 2023
20 min

The Powerful Duo: How Glutathione and Vitamin C IV Drips Impact Cancer

High-dose intravenous (IV) vitamin C has the potential to kill cancer cells and prolong the survival of terminal cancer patients. This podcast is a preview, the full vi

Nov 1 2023
1 min

Chart trend

Position in the Nutrition chart (US), last 90 days.

#1
all-time peak
4
days in the top 3 since Nov 2024

Chart positions

Where Mastering Nutrition ranks today in each Apple Podcasts chart (US, Oct 3, 2026).

#183 ▼ 23 Nutrition US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

I’ve been to 14 doctors who don’t understand ferritin or riboflavin- I know this podcast is not medical advice but it is imperative that if you want optimal health you must educate yourself!! This is a great podcast to start!

robeeenz · Apr 2023

Thanks Chris for the information regarding Covid 19. I am keeping notes. In the event I or someone I know ends is hospitalized I will know what to ask the healthcare professionals and what to keep an eye on. Your podcasts are precise and informative. Information is power and I feel like I have (at least a little bit) of control over this virus.

KSSLC · Apr 2020

Besides doling out $100K for an advanced degree, I know of few other ways to get such quality nutrition education resources. This podcast, and Masterjohn's related resources, provide that education. After getting my master's degree in nutrition, I use Chris Masterjohn's material to keep me up to date with the latest clinical research. I even used his mastering nutrition courses to study for the exam to become a registered dietitian - and his material is even better. Take charge of your health, take charge of your knowldege, and make it engaging and interesting by following Dr. Masterjohn's comprehensive and valuable work! Six stars!

Detrick Snyder · Jun 2019

I've been listening to Chris' Mastering Nutrition, and Masterjohn Lite for years. I've learned so much that I've been able to apply to myself. For example, using a Histamine Blocker to stop headaches has been a godsend for me; and the podcast about collagen, glycine and methylation helped me get my homocystine levels down. I highly recommend Chris' podcasts for everyone who cares about their health.

B.DeBruine · Mar 2019

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About Mastering Nutrition on Reason.fm

Here you find the Apple Podcasts chart positions of Mastering Nutrition, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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