Less of You: Life on Semaglutide & Tirzepatide artwork

Nutrition · Eva Sheie & Kami Gamlem

Less of You: Life on Semaglutide & Tirzepatide

by Eva Sheie & Kami Gamlem

Eva + Kami are two old-ish moms confronting our reasons for being obese while losing weight on semaglutide and tirzepatide, and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast.  After a friend (who is a plastic surgeon) talked Eva into starting semaglutide in February of 2023, she lost 70 pounds in 14 months, alternating between long stretches of being stalled at the same weight and consistent but slow weight loss.  Chasing a lifelong dream to being considered just overweight and not obese by the BMI calculator, after 14 months Eva switched to tirzepatide to try and reach a goal that still seems just out of reach.   A prolific eater of her feelings, Kami was tired of being uncomfortable and when she heard through a mutual friend how semaglutide had changed Eva’s life, she found a trusted medical weight loss provider and took the first step.  As Kami starts her life on semaglutide, Eva adjusts to a world with less food noise and figures out how to let go of the crippling negative self-talk.  On each episode, we connect on how our lives are changing in real time as semaglutide and tirzepatide help us be smaller people, and try to answer the bigger question for ourselves:  When there’s less of you, what is left?

Latest episodes

Showing 20 · updated from the feed

The Scale Is Finally Moving Again

Eva hadn't budged from 186 for a year and a half — until she stepped on it this week and saw 180, a number she hasn't seen in ages, ice cream summer in Washington include

Sep 4
36 min

Do I look better yet?

Three weeks after her Halo resurfacing, Eva decides to take the opportunity to have a Junera laser treatment, a new technology that treats the skin from within to tighten

Aug 21
32 min

Replacing The Microwave (Also Known As The Micro-Wah-Vay)

After an important discussion about the microwave (also known as the micro-wah-vay), we theorize that GLP-1s are basically commoditized now.  Meanwhile, to fix the micro

Aug 14
26 min

I Did Halo Laser Resurfacing On My Way to a Dance Recital

After Eva went in for Halo laser resurfacing with a friend (who happens to be one of the best in the world), she walked out looking horrifying (according to the 8 year ol

Aug 7
30 min

We're Back, and We Found a Cheaper Way to Get Your Meds

After an accidental three-and-a-half-month hiatus, we are back with updates and committing to every week. We catch up on  kids, summer camps, GLP-1 dosing and pricing, HR

Jul 31
45 min

Why you shouldn’t go off meds

Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones. Eva + Kami

Mar 27
31 min

The Dryer Shrunk My Jeans

Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent

Jan 9
29 min

I took a 4 week break from semaglutide and here’s what happened

Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years.

Nov 14 2025
37 min

You Want Fries With That?

After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too. New compounded meds including glycine and B12 make a noticeable

Oct 3 2025
30 min

Replacing one addiction with another?

While working on a project about addiction, Eva realizes she went from drinking and smoking to a food addiction. But she’s not even sure what her “thing” is now, which is

Sep 5 2025
17 min

How to hide that you’re on a GLP-1

If you want to keep your meds a secret from someone you live with, here’s how we would keep it secret.  Kami’s cat, Leonardo Von Flouffe, makes his debut.  Eva remember

Aug 15 2025
47 min

Have we replaced food noise with mom guilt?

How does being hungry seem to interfere with every activity?  One child can’t stop eating sugar, the other starts yelling about being hungry while sitting in the 4th row

Aug 8 2025
36 min

Do GLP-1s Help With Binge Eating?

Ashley tried everything. She tried all the diets: Weight Watchers, Nutrisystem, SlimFast, Houston Methodist Medical Weight Management program. Even after a gastric sleeve

Jul 18 2025
1 h 00 min

Not-So Texas Roadhouses

Kami forgets to track her calories and take her meds. Eva sends her daughter to camp and Kami remembers getting left behind at camp at age 12, back when there were no cel

Jun 20 2025
29 min

Muffin Top, Sleep Apnea, Payment Plans

Eva gained a few pounds back and got a muffin top. Kami vs. insurance: It should not be this hard to get sleep apnea treatment. Yep, you can get a payment plan for weigh

May 23 2025
35 min

No I Don’t Feel Totally Different Now

Kami broke her foot, and can’t move. Eva ate 4 dark chocolate mini eggs and got sick (4 eggs, not 4 bags of eggs). We beat the question “Don’t you feel totally different

Apr 25 2025
20 min

Teetering on the Edge of One-derland

Kami finally busted through the plateau, now hovering at 200 at officially down 50 lbs. Eva’s creeping toward 100 lbs lost,  and had to try on size 8 jeans for the first

Mar 14 2025
24 min

The GLP-1 and addiction connection no one’s talking about with Dr. Jason Giles

In this special bonus episode, an excerpt from a conversation with Los Angeles Addictionologist Dr. Jason Giles about the potential for GLP-1s as a treatment for substanc

Mar 7 2025
46 min

Debra’s 6 month progress update & tips for those with only 15 lbs to lose

The Debra returns with a progress update and fills in for Kami, who’s out with the flu.  She started at 168, now at 154, aiming for 150. It took almost two months before

Feb 14 2025
17 min

Possibly The Worst Before Photo Ever

Kami stalls at 203 and wonders if it’s time for a higher dose to make it to one-derland.  Eva shares a jaw-dropping “before” pic from August 2021 after eating at Paula D

Jan 31 2025
27 min

Chart trend

Position in the Nutrition chart (US), last 90 days.

#92
all-time peak
5
days in the top 100 since Nov 2024

Chart positions

Where Less of You: Life on Semaglutide & Tirzepatide ranks today in each Apple Podcasts chart (US, Sep 16, 2026).

#153 ▼ 12 Nutrition US

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