Race Against Mind: An Alzheimer's Prevention Investigation

Ep. 12 Does Botox Touch the Brain? What the Research Shows for APOE4

I've been getting Botox on and off since I was 38. I never once thought about what it might mean for my brain until another APOE4 carrier asked me directly. So I went loo

Ep. 11 The Accumulation: What I Do When the Research Doesn't Give Me an Answer

This episode is different. No protocol, no experiment, no takeaways in the usual sense. Instead, I'm sitting with what happens when APOE4 research keeps getting more spec

Ep. 10 Chronic Stress, Cortisol & Alzheimer's Risk: The APOE4 Vulnerability No One Talks About

Chronic stress is one of the most underappreciated risk factors for Alzheimer's disease and for APOE4 carriers, the relationship between stress hormones and neurodegenera

Ep. 9 The Perimenopause-Alzheimer’s Connection: HRT, APOE4, and Why Timing Changes Everything

Women account for two-thirds of all Alzheimer’s cases. For a long time, the explanation was simple: women live longer. But that doesn’t fully account for the gap. What th

Ep. 8 The Alzheimer's Risk Factor Hidden in Your Nightly Glass of Wine

I was having a glass of wine most nights when I got my Oura Ring. Not a lot, or so I thought. Within weeks the data told a different story. My HRV baseline runs in the ni

Ep.7 Blueberries, Coconut Oil, and the Mediterranean Diet: What the Nutrition Research Actually Says

Someone told me to give my mom coconut oil after her Alzheimer's diagnosis. My mom couldn't remember I was pregnant at the time. The person meant well. The advice was wro

Ep. 6 APOE4, Cholesterol, and Alzheimer's Risk: What Your Lipid Panel Is Missing

In February of last year, I woke up with brain fog so severe I started researching how to get a brain scan. I was convinced I had amyloid accumulating. I wanted data, not

Ep. 5 Why Keto Backfired: MCT Oil, APOE4, and the Cholesterol I Couldn't Fix With Diet

I've had high cholesterol since I was nine years old. I know, because my mom took away my chicken nuggets and put me on a diet. Three months later it came back to normal.

Ep. 4 The Case for Taking Sleep Seriously: What the Research Says and How to Use Your Data

Sleep is the most underrated lever in brain health. The research is unusually clear: what happens during deep sleep directly affects your risk of cognitive decline, the h

The Exercise Research Every APOE4 Carrier Needs to Hear

This episode goes deep on the exercise pillar. The four mechanisms connecting movement to brain health, including a 2026 UCSF study that identified a liver enzyme that re

How to Build a Baseline and Understand Your Risk

For APOE4 carriers, knowing your risk is only useful if you know what to do with it. In this episode, Sarah walks through her path to developing a baseline, and discusses

APOE4 Positive and Alzheimer's Risk: One Woman's 5-Year Brain Health Protocol

Sarah is homozygous APOE4, the highest genetic risk profile for Alzheimer's disease. Her grandmother had it. Her mother was diagnosed at 58. When she got her own results,