The Human Upgrade: Biohacking for Longevity & Performance artwork

Health & Fitness · Dave Asprey

The Human Upgrade: Biohacking for Longevity & Performance

by Dave Asprey

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

Latest episodes

Showing 20 · updated from the feed

It's Boring, But It Slashed ALL My Visceral Fat In My 50s : 1549

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ I'm in the

Oct 4
19 min

Vagus Nerve Memory, Cat Cancer Genes, Inherited Intelligence, Mulberry Microbes, and Vitamin D : 1548

#50 trending · Health & Fitness

Vagus Nerve Stimulation Improves Cognitive Scores in a Small Trial  In a 24-week trial involving people with mild cognitive impairment, participants assigned to electric

Oct 2
10 min

Dave’s Anti-Aging Skincare Routine: Exosomes, Methylene Blue & NAD+ : 1547

Visit https://www.younggoose.com/ and use code ASPREY10 to save on the skin longevity products discussed in this episode.  Skin Longevity, Cellular Repair, Red Light The

Oct 1
47 min

The Silent Fatty Liver Epidemic: Why Thin, Sober People Are Still at Risk : 1546

Visit LoveYourLiver.com and use code Dave2026 to access the special offer from de-liver-ance mentioned in this episode. Host Dave Asprey sits down with Siggi Clavien, F

Sep 29
56 min

Every Way to Melt Visceral Fat FAST In 14 Minutes : 1545

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevi

Sep 27
14 min

Ozempic Hair, GLP-1 Kids, Gut-Brain Anxiety, Food Additives, Taurine, and more : 1544

Novo Nordisk Eyes Hair-Loss Market in Consumer-Health Expansion  Novo Nordisk, the company behind Ozempic and Wegovy, is exploring hair loss as one of several possible a

Sep 25
14 min

The Best Singular Hack To Change EVERYTHING About Your Life : 1543

Back again with one of the best episodes we've done on the channel. So good that we had to play it once more for you! Today you’ll meet Robert Waldinger, M.D., who leads

Sep 24
1 h 13 min

15g Every Morning for Anti-Aging Mitochondria : 1541

Catharine Arnston on Spirulina, Chlorella, Mitochondria, Detox, Brain Energy, and Longevity  Visit https://energybits.com/ and use code HUMANUPGRADE for 20% off.  Could

Sep 22
58 min

I Wasted 10 Years Stuck With Brain Fog Until I Learned This : 1540

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevi

Sep 20
20 min

Teal Swan - Beyond the Veil of Ego, AI & Wisdom : 1539

Back with another all-time classic. Teal's is one of those episodes I keep going back to because it was just that good. Now more than ever, we need to ask ourselves: what

Sep 18
1 h 02 min

How to Hack Your Smell for Memory and Longevity WHILE YOU SLEEEP! : 1538

Dr. Michael Leon on Smell Training, Memory, Sleep, Alzheimer’s Risk, and Brain Longevity  Your sense of smell may reveal more about your brain health than you realize, a

Sep 17
54 min

Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537

**Visit https://www.gatlan.com/ and use cod ‘DAVE’ to unlock a free consultation!** At 53, Josh Duhamel says he feels better than he did in his 30s.  Host Dave Asprey s

Sep 16
55 min

The Peptide Secrets to a Youthful Face : 1536

Carolina Reis de Oliveira on Reversing Skin Age, Menopause, GLP-1 Skin, and the Science of Senescent Cells  Your skin is likely biologically older than you are, but new

Sep 15
55 min

What 36 Hours Without Sugar Does to Your Body : 1535

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevi

Sep 13
12 min

New Seafood Superfood, Apple Watch Health Age, Botanical Drugs, Cannabis IQ, and Blueberries : 1534

Sea Squirt Plasmalogens Show Brain And Aging Benefits In Old Mice  Aged mice given purified plasmalogen supplements showed better memory performance, healthier synaptic

Sep 11
9 min

Everything You Need To Know About Your Poop | Gut Surgeon Explains : 1533

Dr. Karan Rajan on Fiber Fermentation, Sodium Myths, and What Your Poop Reveals About Disease Risk  Your poop is more predictive than almost any other health signal, and

Sep 8
1 h 09 min

If I Had To Lose 50 Pounds FAST, I’d Do THIS : 1532

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevi

Sep 6
10 min

Raw Garlic, Egg Yolks, Heat Strokes, and Melatonin : 1531

Raw Garlic "Ultimate Biohack" Trend Faces Scientific Scrutiny  Raw garlic has gone viral as a morning ritual, with fans crushing a clove, mixing it with honey, and credi

Sep 4
7 min

Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask : 1530

Jenny McCarthy on Reversing Autism, Healing Mold Toxicity, and the Biohacking Protocol Big Pharma Doesn't Want You to Know  Back with another long one! Autism, mold pois

Sep 3
1 h 58 min

3 Longevity Drugs I QUIT (And the 4 I Take Instead) : 1529

The 3 "Longevity Drugs" That Fail the Data, and 4 Repurposed Ones Worth Considering    Back with another solo episode, this one on Big Pharma! Metformin, rapamycin, and

Sep 1
35 min

Chart trend

Position in the Health & Fitness chart (US), last 90 days.

#25
all-time peak
166
days in the top 50 since Nov 2024

Chart positions

Where The Human Upgrade: Biohacking for Longevity & Performance ranks today in each Apple Podcasts chart (US, Oct 4, 2026).

#80 ▲ 5 Health & Fitness US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

I have been following and listening for over 5 years. I’m incredibly grateful for this podcast and the dedication Dave puts into delivering valuable insights and cutting-edge resources. As a busy entrepreneur with limited time, I’ve come to trust that every guest is thoughtfully selected by Dave and his team. I know I can rely on the content to extract actionable knowledge that aligns with my life, health, and longevity goals. Over the years, this podcast has deepened my understanding of the body and empowered me to take an active role in my own health decisions. Thank you, Dave, for the time, expertise, and effort you invest—it has truly made a lasting impact on my life. Laure Hardman

LD Events · Mar 2025

I’ve been on my healing journey for five years. I’ve read over 140 books on cellular healing and biohacking and follow the podcasts of both Asprey and Brecka for years. This two-part interview is the best. Well done, gents.

Doug and Kate · Feb 2025

Highly recommend! Dave has a very entertaining way of presenting science around many different areas of our metabolism and longevity while also interjecting his dry humor throughout each episode.

KaitlinBeManifesting · Jan 2025

I have been listening to this podcast for more years than I can count and I always learn something new every episode! Dave is kind and intelligent and brings on the most thought provoking guests full of insightful information. I will keep listening for as long as Dave has podcasts!

lakelady16 · Aug 2024

As the title says, every show either the author or the guest for both are trying to sell you something. Take everything with a grain of salt. They’re not backing up their claims with good research. They’re taking small studies, sometimes not even in humans, and making huge claims that just isn’t supported by the data. I was really looking for a fresh perspective, the one that is evidence based. One thing, however, we can all agree upon is that processed foods in the American diet is harmful.

BozieOzzie · Jul 2024

I find this podcast pretty informative but I’m listening to learn from the people mr asprey is interviewing. Instead, you mostly hear mr asprey talking about himself, pimping his products, and commandeering the whole podcast. If you count all his sentences in a podcast, I guarantee that he talks twice as much as the person he’s interviewing. This seems to be a common theme among the popular podcasters lately. I’m just not listening to it anymore.

Rachel3601 · Jul 2024

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Here you find the Apple Podcasts chart positions of The Human Upgrade: Biohacking for Longevity & Performance, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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