The Human Upgrade: Biohacking for Longevity & Performance artwork

Health & Fitness · Dave Asprey

The Human Upgrade: Biohacking for Longevity & Performance

by Dave Asprey

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

Latest episodes

Showing 20 · updated from the feed

Immortal Jellyfish, Fructose & Cancer, Cleaner Air for Blood Sugar, Carbon Dioxide for Alzheimer's, and More : 1573

Scientists Test Carbon Dioxide Exposure To Help Clear Alzheimer's-Related Proteins From The Brain Researchers at the University of New Mexico are investigating whether i

Nov 13
11 min

The Hidden Health Warnings in Your Poop (And Why You Should Look) | Chloe Melas : 1572

Get Chloe's book The Girl’s Guide To Guts at thegirlsguidetoguts.com  Gut microbiome, stool testing, colon cancer warning signs, ulcerative colitis, chronic constipation

Nov 12
1 h 07 min

Why Your Brain Craves Things That Make You Miserable | Luke Storey : 1571

Get your copy of Luke’s new book: A Horse Named Lonesome https://ahorsenamedlonesome.com  The Neuroscience of Addiction, Breaking Bad Habits, Childhood Trauma, Psychedel

Nov 10
1 h 06 min

15 Minutes Every Morning Kills Insulin Belly Fast : 1570

There's a 15 minute habit you can do every morning that kills insulin belly. That's the fat packed around your organs. It drains into your liver, forces your body to make

Nov 8
16 min

Brain-Cleaning Beds, Forever Chemicals, Peptide Freedom, Coffee for Your Heart, and More : 1568

Scientists Test Vibrating Mattress To Help Clear Alzheimer's-Related Proteins From The Brain  Researchers at the University of Oulu in Finland tested a vibrating mattres

Nov 6
10 min

How to Get Really Good at Anything: The 3 Ingredients of Mastery | Roman Tsunder : 1569

Get Roman Tsunder's book and learn more at https://pttow.com/  How to Master Any Skill, the Science of Peak Performance, Obsession, Deep Focus, Finding Your Purpose, Ove

Nov 5
58 min

The Truth About Vitamins, Supplements & Prescription Drugs | Phil Cowley : 1567

Triquetra Discount: Use code Dave20 at Triquetrahealth.com/dave  Multivitamin Mistakes, MTHFR Genetics, B Vitamins, Creatine & Prescription Drug Risks  Host Dave Asprey

Nov 3
1 h 07 min

I Tried EVERY Controversial Focus Drug : 1566

I've tried every controversial focus drug I could get my hands on. Modafinil, LSD, psilocybin, mescaline, DMT, ketamine, MDMA, amphetamine, ephedrine, the racetams, and a

Nov 1
38 min

Placebo Pills, Cannabis, Wall Squats for Blood Pressure, Birdwatching, and the Porn brain : 1564

Placebos Improved IBS Symptoms Even When Patients Knew the Pills Were Inactive In a randomized trial of 80 adults with irritable bowel syndrome, participants who knowing

Oct 30
10 min

The No-Brainer Solution To Stop Overeating : 1565

Use Dave10 at calocurb.com to get a discount  How Hops Extract Suppresses Hunger, Reduces Cravings, Supports Weight Loss, and Makes Intermittent Fasting Easier Host Dav

Oct 29
51 min

The Easiest Treatment That Made Me 15 Years Younger : 1563

Explore House of Evolution: https://daveasprey.com/house-of-evolution/  Host Dave Asprey sits down with Dr. Tim Cook, a physician and longevity medicine expert who previ

Oct 27
43 min

How To Reverse Your Age For $5 Day (Budget Biohacking) : 1562

I have spent $2.5 million on this body, and Bryan Johnson spends about $5,400 a day on his. But does it need to be that expensive to biohack? So I gave myself a challenge

Oct 25
24 min

Avoid THESE "Healthy" Superfoods : 1561

We just had to bring this one back for you. Today, we’re digging once again into specifics about food that you haven’t heard on the show before. This one may very well in

Oct 23
1 h 15 min

How to Trigger Flow States From The 5 Brain Chemicals You Need : 1559

The Neuroscience of Flow, Peak Performance, Psychedelics, Trauma, Intuition & Consciousness with Steven Kotler Host Dave Asprey sits down with Steven Kotler, New York Ti

Oct 22
56 min

The 6-Minute Morning Routine That Can Change Your Life : 1558

The Miracle Morning, Visualization, Affirmations, Meditation, Morning Routines, Productivity & the Psychology of Success with Hal Elrod Host Dave Asprey sits down with H

Oct 20
48 min

400mg Before Bed Improves Deep Sleep by 1700% : 1557

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ I slept 8 h

Oct 18
13 min

John Gray: Why Men Stop Wanting Their Wives : 1556

The king is back! You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus.  But what's especially exciting is how John

Oct 16
1 h 45 min

Sleep Expert: 80% of Sleep Problems Come From THIS : 1555

Sleep Anxiety, Insomnia, Circadian Rhythms, Chronotypes, Sleep Trackers & How to Sleep Better with Dr. Michael Breus  Host Dave Asprey sits down with Dr. Michael Breus,

Oct 15
40 min

The Science Behind Joint and Cartilidge Repair : 1554

Explore Calroy's vascular health and joint support supplements, including Arterosil, Vascanox, and Cartigenix, at https://calroy.com/dave  Cartilage Regeneration, Joint

Oct 13
49 min

Your Brain Has a Focus Switch (Here's How to Turn It On) : 1553

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ This video

Oct 11
18 min

Chart trend

Position in the Health & Fitness chart (US), last 90 days.

#19
all-time peak
176
days in the top 50 since Nov 2024

Chart positions

Where The Human Upgrade: Biohacking for Longevity & Performance ranks today in each Apple Podcasts chart (US, Nov 15, 2026).

#25 ▼ 2 Health & Fitness US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

I have been following and listening for over 5 years. I’m incredibly grateful for this podcast and the dedication Dave puts into delivering valuable insights and cutting-edge resources. As a busy entrepreneur with limited time, I’ve come to trust that every guest is thoughtfully selected by Dave and his team. I know I can rely on the content to extract actionable knowledge that aligns with my life, health, and longevity goals. Over the years, this podcast has deepened my understanding of the body and empowered me to take an active role in my own health decisions. Thank you, Dave, for the time, expertise, and effort you invest—it has truly made a lasting impact on my life. Laure Hardman

LD Events · Mar 2025

I’ve been on my healing journey for five years. I’ve read over 140 books on cellular healing and biohacking and follow the podcasts of both Asprey and Brecka for years. This two-part interview is the best. Well done, gents.

Doug and Kate · Feb 2025

Highly recommend! Dave has a very entertaining way of presenting science around many different areas of our metabolism and longevity while also interjecting his dry humor throughout each episode.

KaitlinBeManifesting · Jan 2025

I have been listening to this podcast for more years than I can count and I always learn something new every episode! Dave is kind and intelligent and brings on the most thought provoking guests full of insightful information. I will keep listening for as long as Dave has podcasts!

lakelady16 · Aug 2024

As the title says, every show either the author or the guest for both are trying to sell you something. Take everything with a grain of salt. They’re not backing up their claims with good research. They’re taking small studies, sometimes not even in humans, and making huge claims that just isn’t supported by the data. I was really looking for a fresh perspective, the one that is evidence based. One thing, however, we can all agree upon is that processed foods in the American diet is harmful.

BozieOzzie · Jul 2024

I find this podcast pretty informative but I’m listening to learn from the people mr asprey is interviewing. Instead, you mostly hear mr asprey talking about himself, pimping his products, and commandeering the whole podcast. If you count all his sentences in a podcast, I guarantee that he talks twice as much as the person he’s interviewing. This seems to be a common theme among the popular podcasters lately. I’m just not listening to it anymore.

Rachel3601 · Jul 2024

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Here you find the Apple Podcasts chart positions of The Human Upgrade: Biohacking for Longevity & Performance, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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