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Alternative Health · Prime Longevity Protocol

Weekly Pep Talk

by Prime Longevity Protocol

Welcome to Weekly Pep Talk — where GLP-1s, peptides, and longevity get real and judgment-free. Hosted by Prime Longevity Protocol, each episode covers semaglutide, tirzepatide, peptide therapy, biohacking, weight loss, metabolic health, and wellness optimization. Real talk for Warriors who refuse to settle for average. No shame. No gatekeeping. Just real people chasing real results. New episodes every week. Come optimize with us. 🧬 Nothing discussed is medical advice. Always consult your healthcare provider.

Latest episodes

Showing 20 · updated from the feed

RETA Update: FDA battle continues, New Reta addition, MK677, PCOS & Q&A

MK-677, Retatrutide, growth hormone, peptide sourcing, testing, PE-22-28 and PCOS — this episode of Weekly Pep-Talk covers a wide-ranging Q&A on some of the most talked-a

Sep 28
53 min

How to Stay Shredded Year-Round: Peptides, Fat Loss, Muscle & Recovery

What if you didn't have to wait until summer to get lean, shredded, and beach ready? In this episode of Weekly Pep-Talk, Mike Sheffer and Max Plasencia take the conversa

Sep 21
56 min

The Future of Weight Loss Peptides + ARA-290 for Nerve Recovery | Mike Sheffer & Max Plasencia | Ep. 25

What happens when peptide recovery protocols meet the next generation of weight-loss compounds? In this episode, Mike Sheffer and Max Plasencia dive into some of the big

Sep 14
52 min

New Retatrutide Is Coming? Peptide Reactions & HGH vs. IGF-1 | Mike Sheffer & Max Plasencia

The peptide landscape is changing fast and retatrutide is at the center of the conversation. In this episode, Mike Sheffer and Max Plasencia discuss the latest developme

Sep 7
56 min

Peptides vs. Bioregulators: What's the Difference & Which Is Better?

What is the difference between peptides and bioregulators, and could bioregulators represent the next evolution of peptide therapy? In Episode 23, Max Plasencia and Mike

Aug 31
55 min

The Future of Peptides: Retatrutide, Muscle Growth, HGH & Longevity | Mike Sheffer & Max Plasencia

Welcome back to another episode of Weekly Pep-Talk with Mike Sheffer and Max Plasencia. In this episode, Mike and Max break down the rapidly changing peptide landscape,

Aug 25
55 min

Sign in Inside the Peptide Industry: Testing, Quality, Safety & What Comes Next

What really happens behind the scenes in the peptide industry?In this episode, Trevor Kruder sits down with Michael Sheffer and Max Plasencia for a deep discussion about

Aug 21
1 h 45 min

The Health Problems Hiding in Your Body: Parasites, Liver Detox, Water & Peptides | Ariel Jarvis

Welcome back to another episode of Weekly Pep-Talk This week, Mike sits down with Ariel Jarvis, a natural health practitioner, herbalist, nutritionist, Traditional Chine

Aug 17
1 h 30 min

Your Blood Work Is Missing This! Triglycerides, A1C, VIP & Peptides | Mike Sheffer & Max Plasencia

Welcome back to another episode of Weekly Pep-Talk with Mike Sheffer and Max Plasencia. This episode is all about blood work, metabolic health, peptides, inflammation, a

Aug 10
52 min

Can Peptides Improve Fertility? + Breaking GLP-1 Weight Loss Plateaus | Mike Sheffer & Max Plasencia | Ep. 19

Welcome back to another episode of Weekly Pep-Talk! In Episode 19, Mike Sheffer and Max Plasencia dive into one of the most requested topics in the peptide community: fe

Aug 3
49 min

Traveling with Peptides + The Future of Bioregulators. Pep-Talk Ep. 18

Welcome back to another episode of Weekly Pep-Talk! In Episode 18, Mike Sheffer and Max Plasencia answer one of the most frequently asked questions in the peptide commun

Jul 27
47 min

Women's Health After 40: Menopause, GLP-1s & Peptides | Mike, Max & Jeri Mermini Ep. 17

In this episode of weekly pep talk, we sit down with Jeri Mermini. Jeri is a mom of two, hairstylist, and makeup artist with a passion for fitness, nutrition, beauty, and

Jul 20
59 min

Peptide Q&A: Injection Sites, Hashimoto's & Menopause | Mike Sheffer & Max Plasencia| Pep-Talk Ep 16

Welcome back to another episode of Weekly Pep-Talk! In Episode 16, Mike Sheffer and Max Plasencia answer some of the most frequently asked questions from the peptide com

Jul 13
1 h 02 min

Weight Loss, Autoimmune Disease & Injury Recovery | Mike Sheffer & Max Plasencia | Pep-Talk Ep. 15

Welcome back to another episode of Weekly Pep-Talk! In Episode 15, Mike and Max answer some of the most common questions from the peptide community, covering everything

Jun 29
47 min

Episode 14: Dan Solomon on Mr. Olympia, WINFUEL, Peptides & The Future of Bodybuilding

This is a special episode of Weekly Pep-Talk. Max and Mike sit down with Dan Solomon, President of Mr. Olympia, the fitness industry’s premier bodybuilding competition,

Jun 22
1 h 12 min

Peptides vs Big Pharma- Who Controls The Future

What happens when you combine peptides, fasting, brain optimization, and the future of medicine into one conversation? In Episode 13 of Weekly Pep-Talk, Max and Mike div

Jun 15
1 h 04 min

The “Research Use Only” Peptide Truth Nobody Explains

What does “research use only” actually mean when it comes to peptides — and what are people getting wrong? In this episode of Weekly Pep-Talk, Max and Mike Sheffer break

Jun 8
1 h 13 min

25% Of The Peptides We Tested Were FAKE | Real Lab Results

Are the peptides you’re buying actually real? In this bonus episode of Weekly Pep-Talk, Max Plasencia and Mike Sheffer reveal the results of a real peptide testing exper

Jun 2
55 min

Best Summer Shred Peptide Stack + Tesamorelin Experiment

What’s the best peptide stack to get shredded for summer without losing muscle, energy, or your hair? In Episode 10 of Pep-Talk, Max Plasencia and Mike Sheffer break dow

Jun 1
49 min

Cancer Peptides, TRT & Longevity Hacks Q&A

Can peptides improve longevity, optimize TRT, boost energy, and even support cancer recovery protocols?In Episode 9 of Pep-Talk, Max Plasencia and Mike Sheffer answer lis

May 25
51 min

Chart trend

Position in the Alternative Health chart (US), last 90 days.

#85
all-time peak
2
days in the top 100 since Jul 2026

Chart positions

Where Weekly Pep Talk ranks today in each Apple Podcasts chart (US, Sep 29, 2026).

#185 ▼ 17 Alternative Health US

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About Weekly Pep Talk on Reason.fm

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