Intention to Treat

The Long Haul of Long Covid

This episode explores long Covid, an often-disabling but unexplained syndrome of post-acute sequelae of SARS-CoV-2. How is it affecting millions of people, and what is be

What We Don’t Know about School Shooter Drills

This episode peers into U.S. schools to examine a widespread but non–evidence-based approach to preparing children and staff for gun-violence incidents. A full transcrip

Awakened Hope for Narcolepsy

In this episode, a patient with narcolepsy describes her rough, long road to diagnosis and treatment, and a researcher elucidates both the condition and a new therapeutic

Obesity and Heart Failure

Cardiologists now recognize that heart failure with preserved ejection fraction (HFpEF) may be caused by obesity. This episode of “Intention to Treat” examines new eviden

Preventing HIV’s Collateral Cardiovascular Damage

People living with HIV have increased risk for cardiovascular disease (and other diseases of aging) earlier in life than those without HIV. In this episode of “Intention

Prospects for Pain

Some types of pain have proven resistant to all available medications. In this episode of “Intention to Treat,” Rachel Gotbaum talks with a patient with neuropathic pain

The Plight of Primary Care, Part 2

What is driving U.S. physicians out of primary care — and keeping trainees from going into it in the first place? In this episode of “Intention to Treat,” host Rachel Got

The Plight of Primary Care, Part 1

This episode of “Intention to Treat,” explores the crisis in primary care in the United States, as increasing numbers or primary care physicians leave the field — driven

Unleashing CRISPR on Cancer

In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and t

New Patient-Centered Options for Cancer Treatment

“Intention to Treat” host Rachel Gotbaum talks with patient Awilde Peña and oncologist Deb Schrag about a new approach to treating rectal cancer that sidesteps the need f

Lessons for a Pandemic

In this episode of “Intention to Treat,” Drs. Harvey Fineberg and Eric Rubin take stock of the failures and successes of the Covid-19 response and elucidate their lessons

Race Relations and the First Paramedics

This episode of “Intention to Treat” tells the story of the Freedom House Ambulance Service — a group of Black laypeople in Pittsburgh who underwent intensive training to

Waiting on Prostate Cancer

In this episode of “Intention to Treat,” host Rachel Gotbaum talks with patient Robert Schlamberg and Doctors Oladapo Yeku and Oliver Sartor about the option of watchful

Is Medicine Ready for AI?

In this episode of “Intention to Treat,” Maia Hightower and Isaac Kohane join host Rachel Gotbaum to explore the promise and hazards of artificial-intelligence and machin

The Fauci Phenomenon, Part 2

In this episode of “Intention to Treat,” Anthony Fauci sits down with host Rachel Gotbaum to discuss his long career in infectious disease and public health, what has mot

The Fauci Phenomenon

In this episode of “Intention to Treat,” some of the people who have worked closely with “America’s Doctor,” Anthony Fauci, offer insights into his character, values, acc

The Promise and Perils of Psychedelics

In this episode of “Intention to Treat,” a study participant and a long-time investigator of hallucinogenic drugs for psychiatric conditions illuminate the effects of psi

Post-Roe Realities

In this episode of “Intention to Treat,” host Rachel Gotbaum takes us to Tennessee and Ohio, where new abortion bans are already harming patients and threatening their ph

Covid Vaccines — Playing the Long Game

In this first episode of “Intention to Treat,” NEJM editor-in-chief Eric Rubin and his colleague at the FDA Vaccine Advisory Committee, Paul Offit, consider the achieveme

Trailer: NEJM Group Presents “Intention to Treat”

From the New England Journal of Medicine, welcome to “Intention to Treat,” a podcast exploring the most complicated, perplexing, and fascinating issues facing medicine to