The Curious Clinicians

[Archive] The Smell of the Rain

In the waning days of summer, we at The Curious Clinicians were in the mood take things back to the rains of spring. This episode is a reboot from our archives of one ori

130 - The Simp with Roshan Sethi

This week, Dr. Roshan Sethi joined us for a conversation about his new book, The Simp, balancing life as a director, author, and radiation oncologist, and a bit about his

129 - Ironing Out More Platelets

In this episode, Tony walks us through the surprising physiology behind a phenomenon many of us see every day: Why does iron deficiency cause thrombocytosis? Click here

128 - After Shock with Dr. Rana Awdish

In this episode, we talk curiosity, healing, and the wonders of the human body with Dr. Rana Awdish, bestselling author of In Shock: My Journey from Death to Recovery and

127 - ACHOO! (The Sunlit Sneeze)

In this episode, Avi achoo-ses an seasonal question: Why can sunlight exposure induce sneezing?? Click here for show notes and click here to obtain AMA PRA Category 1 C

126 - A Third Circulatory System

What are the Hidden Pathways in the Human Body? This week, Avi fills us in on the science behind his New York Times Magazine article (link) describing the interstitium

125 - Why Comics?

This week, we talk with Dr. Grace Farris, who is a hospitalist and the author of See One, Do One, Teach One: The Art of Becoming a Doctor: A Graphic Memoir. We explore ho

Why Does Umami Taste So Good?

Today, we are rebooting an absolute classic from way back in our catalog - episode 9. Avi teaches us about the biology behind the taste of umami and why we might have evo

124 - One of the Fastest Reactions in the Human Body

Why don't interstitial lung disease patients typically get increased pCO₂? The answer involves one of the fastest chemical reactions in the human body. Click here for s

123 - Why-roid

In this neck(st) episode, Avi asks an isthmus-ing question: Why does an autoimmune antibody stimulate the thyroid in Graves disease? Click here for show notes and click

[Archive] Irregularly Irregular

We apologize for the break in our regularly scheduled programming! This is a reboot of Episode 77, originally posted in September 2023, which asked: why is hyperthyroidis

[Archive] More Right Than Left

This is a reboot of Episode 66, originally posted back in March 2023, where investigated why tricuspid valve endocarditis is more common in persons who inject IV drugs.

122 - When CRP Goes Missing

This week, Tony shares a morning report physiology pearl: Why do patients with active lupus have a low CRP? Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours)

Reboot! Bendopnea

Cold and flu season greetings from the Curious Clinicians! We hope you all are cold-free, but we were unfortunately under the weather this week. In honor of our "heme boa

121 - The Forgotten Factor

This week, Hannah shares the story of an overlooked piece of the coagulation cascade, beginning with a 1950s medical mystery: Why didn't John Hageman bleed? Click here 

120 - No Sleep for the Weary

This week, Avi shares the pathophysiology behind an important question: Why can't people with familial fatal insomnia fall asleep? Click here to obtain AMA PRA Category

119 - While My Liver Gently Weeps

This week, Tony explores a fascinating, hospital rounds-ready question: Why does cirrhosis cause low SAAG ascites? You can read the show notes here! Click here to obt

118 - Extremophiles

This week, Avi follows up Episodes 112 and 114 with the question: How does a bacterial species called Deinococcus radiodurans withstand extreme levels of radiation? You

117 - The Body A-Z with Dr. Mike Todorovic

This week, Dr. Mike Todorovic returns as a special guest to tell us about his book with Dr. Matt Barton, The Body A-Z! Join us as Dr. Mike gives us a sneak preview of t

116 - Ammonia Rising

This week, Tony brings us a question straight from the hospital wards: Why does valproic acid cause elevated ammonia? You can read the show notes here! Click here to