Hart2Heart with Dr. Mike Hart

#237 Oral Health, Blood Pressure, and Better Hygiene: Dr. Eilon on Toothpaste, Mouthwash, and Whitening

Dr. Mike Hart sits down with Dr. Ilon Choai to unpack everyday dental habits and the connection between oral and overall health. They discuss choosing toothpaste, fluorid

#236 The Cannabis Cure Controversy: Lee Whitley's Bold Claims

In this episode, Dr. Mike Hart sits down with Lee Whitley and physician Dr. Ira Price for a wide-ranging discussion about Lee's proprietary cannabis formulation and the e

#235 Dr. Kenealy on Preventing Cancer: Lifestyle, Toxins, Hormones, Fasting, and Screening Beyond Tumors

In this episode, Dr. Mike Hart sits down with Dr. Leigh Erin Connealy for a wide-ranging conversation on cancer prevention and the factors she believes influence long-ter

#234 Navigating Weight Loss: Breaking Down Barriers with Dan Go

After a five-year hiatus, Dan Go returns to break down a sustainable approach to fat loss for busy people who do not have hours to spend in the gym. He explains why ident

#233 Understanding NAD+: Insights with Dr. Charles Brenner

Charles Brenner breaks down what the science actually says about NAD+, separating established findings from the claims commonly made in the longevity space. He explains w

#233 Understanding NAD+: Insights with Dr. Charles Brenner

Charles Brenner breaks down what the science actually says about NAD+, separating established findings from the claims commonly made in the longevity space. He explains w

#232 Testosterone Screening, Metabolic Health, and Hormone Optimization: Free T, SHBG, hCG, and Body Composition

This episode explores the opportunities and risks of testosterone optimization, beginning with the US military's decision to screen men over 30 for low testosterone. Dr.

#231 Dr. Kyle Gillett on Nootropics, Peptides, GLP-1 Side Effects, Hair Loss, and Microplastics

Dr. Kyle Gillett joins Dr. Mike Hart to discuss safer, more practical approaches to biohacking, performance, and longevity. They cover indoor microplastic exposure, broma

#230 Progesterone for Sleep, GLP-1 Microdosing, and HRT/Peptide Insights with Dr. K

Dr. Mike Hart welcomes Ksenia Petrushkina back for a wide-ranging conversation about using hormones, GLP-1 medications, and peptides more thoughtfully. They explore why l

#229 Supplements, Methylation, and Genetics: Why "Healthy" Stacks Can Trigger Anxiety

Dr. Tyler Panzner joins Dr. Mike Hart to explain how genetics, supplement combinations, and individual brain chemistry can influence anxiety, irritability, brain fog, and

#228 Minoxidil for Hair Loss: Topical vs Oral, Tretinoin, and Microneedling

The episode explains how to use minoxidil for hair loss, emphasizing that it supports follicles and prolongs the anagen phase but does not block DHT (with topical dutaste

#227 Diet Update: High-Protein, High-Fiber Meal Plan Built for Training and Consistency

The speaker shares a structured, consistent diet designed to support hard training (three strength sessions, Norwegian 4x4, Zone 2 cardio, and one MMA session weekly), re

#226 Viewpoint Diversity, Physician-Assisted Suicide, AI, and Human Dignity in Medicine

Dr. Kristin Collier joins Dr. Mike Hart to discuss the ethical, cultural, and technological forces reshaping modern medicine. Reflecting on the 2022 white coat speech wal

#225 GLP-1 Masterclass: Dosing, Optimal Use, Lifestyle Changes, and Benefits Beyond Weight Loss

This episode explores how to use GLP-1 medications like semaglutide/Ozempic and tirzepatide/Mounjaro safely and effectively. Dr. Mike Hart and Dr. Christle Guevarra Do di

#224 Dr. Alex Tatum on Peptides, FDA Crackdowns, TRT Nuance, and Safe Penis Enhancement

Dr. Mike Hart interviews board-certified urologist Dr. Alex Tatum about peptide access, compounding, and men's health. Tatum argues many peptides are naturally occurring

#223 How I Increased My VO2 Max at 41 With the Norwegian 4x4 Protocol

The host explains how he raised his estimated VO2 max in 2026 in his 40s, emphasizing that the biggest driver was structured hard training with progressive overload, not

#222 Peptides, Hormones, and Longevity: Safety, Skin Aging, NAD+, GLP-1s, and Mitochondrial Health with Dr. Ksenia

Dr. Ksenia Petrushkina joins Dr. Mike Hart for a deep dive into regenerative medicine, peptides, hormones, IV therapies, and longevity. They discuss what conventional med

#221 Acute vs. Chronic Inflammation: Causes, Biomarkers, and How to Lower It

The episode explains that inflammation is a necessary survival mechanism, with acute inflammation supporting healing, while chronic inflammation drives chronic disease. I

#220 Wnt vs DHT: Understanding Androgenic Alopecia and the Top Treatments to Slow Hair Loss

In this solo episode on androgenic alopecia, the host explains that hair loss is slow and progressive, driven largely by genetics and DHT-mediated miniaturization of foll

#219 Dr. Allen Frances on AI Chatbots, Mental Health Risks, Privacy, and the Overdiagnosis of Autism

Dr. Allen Frances discusses how AI chatbots can provide effective support for everyday stress and mild symptoms, with tens of millions using them, but warns they can be d