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Chapter Twenty-Three: Hypoosmolal States–Hyponatremia

Roger’s Hydrogen to pH table References December 19, 2023 Joel had a patient with severe hypothyroidism and hyponatremia- case report Mel reviewed the endocrine facto

Chapter Twenty-Two: Introduction to Disorders of Osmolality

References This is the famous Edelman equation from JCI in 1958 by Isodore Edelman! Interrelations between serum sodium concentration, serum osmolarity and total exchang

Chapter Twenty: Respiratory Acidosis

References Biff Palmer! Respiratory Acidosis and Respiratory Alkalosis: Core Curriculum 2023 Josh what is sensed- pCO2 or pH and some exploration suggests that it is no

Chapter Twenty One: Respiratory Alkalosis

References Chapter 19, Part 3 August 30, 2023Biff Palmer’s Ted Talk-Why not? Biff Palmer at TEDxSMU 2013 Anna mentioned this issue of lactic acidosis in a panic disorde

Chapter Nineteen: Metabolic Acidosis, part 3

References Chapter 19, Part 3 August 30, 2023 Joel and Roger mentioned the most common cause seems to be Sjögren’s syndrome for an acquired distal RTA. We mentioned thi

Chapter Nineteen: Metabolic Acidosis, part 2

References Chapter 19, Part 12 Metabolic acidosis  June 14, 2023 References Chapter 19, Part 2 Roger mentioned MELAS syndrome MELAS syndrome: Clinical manifestations

Chapter Eighteen: Metabolic Alkalosis, part 2

References Part 2, March 1, 2023 The alkaline tide phenomenon in studies that measured both the alkaline tide and acid secretion, the bicarbonate accumulation increased

Chapter Nineteen: Metabolic Acidosis, The Show, part 1

References Chapter 19, Part 1  Metabolic acidosis  June 14, 2023 American Society of Nephrology | Medical Students - Kidney TREKS this is the program that Josh mention

Chapter Eighteen: Metabolic Alkalosis, part 1

We are a bit slappy at the beginning of the episode since we had just recorded our conversation with the Glaucomfleckens. References Chapter 18 Metabolic alkalosis! 

Chapter Seventeen: Introduction to Simple and Mixed Acid-Base Disorders

References I said I used MDCalc but I was mistaken I use MedCalX which is nice but getting dated.  We talked about this out of print book that we love: Cohen, J. J., Ka

Chapter Sixteen: Edematous States, part 2

References We talked about winning the 2022 ASN innovation contest and here’s a link to our promo video https://www.dropbox.com/scl/fi/g4osnf0nradsfryyo51fi/ASN-Educatio

Chapter Sixteen: Edematous States, part 1

References Capillary Hemodynamics  Insights into Salt Handling and Blood Pressure | NEJM Amy mentioned about the 3 phases of the interstitium Are the precapillary sphi

Chapter Fifteen: Clinical Use of Diuretics, part 2

References Proximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice Melanie is in

Chapter Fifteen: Clinical Use of Diuretics, part 1

Outline Chapter 15 — Clinical Use of Diuretics - Among most commonly used drugs - Block NaCl reabsorption at different sites along the nephron - The ability to induce

Chapter Fourteen: Hypovolemic States, part 2

Outline Chapter 14 — Treatment - Treatment - Both oral and IV treatment can be used for volume replacement - The goal of therapy are to restore normovolemia - And

Chapter Fourteen: Hypovolemic States, part 1

Outline Chapter 14 - Hypovolemic States - Etiology - True volume depletion occurs when fluid is lost from from the extracellular fluid at a rate exceeding intake -

Chapter Thirteen: Meaning and Application of Urine Chemistries

References JC mentioned that the diagnostic accuracy of 24 hour urine collection increases with more collections! Metabolic evaluation of patients with recurrent idiopat

Chapter Eleven: Regulation of Acid-Base Balance, part 2

References We considered the complexity of the machinery to excrete ammonium in the context of research on dietary protein and how high protein intake may increase glome

The 2023 NKF Clinical Meeting Live Recording: Diuretic Draft

The Channelers went where no nephrology podcasters have gone before, recording in front of a live audience at the National Kidney Foundation Clinical Meeting in Austin. W

A Very Special Episode: Meet the Glaucomfleckens