MeSsy with Christina Applegate & Jamie Lynn Sigler

Latest episodes

Showing 20 · updated from the feed

How to Live With What You Can’t Control with Ana Rodriguez

In the final episode of Living With It, Jamie sits down with her therapist, Ana Rodriguez, to talk about what it really means to heal when life doesn’t go according to pl

Sep 24
59 min

The Hardest Fight Is Learning to Rest with Alberto Crane

#29 trending · Personal Journals

This week, Jamie sits down with jiu-jitsu champion and former UFC fighter Alberto Crane to talk about how his MS diagnosis forced him to redefine what it means to be stro

Sep 22
41 min

Stop Apologizing for Wanting More with Heather Dubrow

This week on Living With It, Jamie sits down with Heather Dubrow for an honest conversation about embracing life’s pivots, protecting your peace, and giving yourself perm

Sep 17
54 min

There Is Beauty Within All of This Pain with Lindsey Kraft

This week on MeSsy, Jamie sits down with her longtime friend, actress, writer, and musician Lindsey Kraft. They talk about growing up together, navigating rejection and s

Sep 15
54 min

Falling Apart to Come Back Together with Ryan Weiss

This week on Living With It, Jamie sits down with her friend, Ryan Weiss. They talk about letting go of control, sitting with difficult emotions, knowing when it’s time t

Sep 10
47 min

Thank God I’m So Neurotic with Cat Cohen

This week on MeSsy, Jamie sits down with comedian, actor, and singer Cat Cohen. Cat opens up about having a stroke at 31, navigating health anxiety in the aftermath, and

Sep 8
47 min

We Fight For Joy with Kelsey Chittick

This week on Living With It, Jamie sits down with Kelsey Chittick to talk about losing her husband suddenly, raising two children through grief, and learning to build a l

Sep 3
53 min

There’s No Place Like Home with Annie Meyers-Shyer

This week, Jamie is joined by her longtime friend Annie Meyers-Shyer, the creator behind This Oak House. They talk about Annie’s unexpected second act, finding a new pass

Sep 1
53 min

The Power of Radical Acceptance with Jim Curtis

This week on Living With It, Jamie sits down with Jim Curtis, a transformational coach, author, and wellness leader. They discuss how to radically accept the life you hav

Aug 27
53 min

Jamie's Son Beau

This week, Jamie sits down with a very special guest: her 13-year-old son, Beau. They have an honest conversation about what it’s been like growing up with a mom who has

Aug 25
42 min

Accept, Adapt, Appreciate with Odette Annable

This week on Living With It, Jamie sits down with her friend Odette Annable. They discuss parenting a neurodivergent child, trusting your instincts, advocating for your f

Aug 20
54 min

The Courage to Slow Down

This week on MeSsy, Jamie opens up about reaching her limit and learning to make rest part of healing. She also reads listener emails about fighting to be heard by doctor

Aug 18
53 min

Finding Stillness When Life Won’t Slow Down with Bob Roth

This week on Living With It, Jamie sits down with Bob Roth, a leading Transcendental Meditation teacher and CEO of the David Lynch Foundation. They discuss what stress do

Aug 13
1 h 00 min

How Death Informs How We Live with Julie McFadden

This week, Jamie sits down with hospice nurse Julie McFadden to talk about changing the way we think about death, what she’s learned from those at the end of life, and ho

Aug 11
58 min

Trusting the Journey with Becca Tobin

This week, Jamie sits down with one of her best friends, Becca Tobin, for a conversation about infertility, pregnancy loss, surrogacy, and finding hope after years of unc

Aug 6
57 min

Try to Find the Light with Amanda Kloots

This week, Jamie sits down with Amanda Kloots for an honest conversation about finding joy alongside heartbreak. Amanda opens up about losing her husband, Nick Cordero, h

Aug 4
59 min

Look for the Signs with Kate Doerge

On this episode of Living With It, Jamie sits down with Kate Doerge to discuss finding hope after profound loss, recognizing signs from loved ones, and the five actions t

Jul 30
58 min

Hope Can Exist Alongside Fear with Myriam Sandler

This week, Jamie sits down with Mothercould creator Myriam Sandler. They discuss her recent MS diagnosis, trusting your intuition, and finding hope even when life doesn't

Jul 28
1 h 07 min

It's Okay Not to Be Okay with Amy Kurtz

On the first episode of Living With It, Jamie sits down with Amy Kurtz, a patient advocate and author. They discuss the grief of chronic illness, learning to trust yourse

Jul 23
55 min

All Eyes on Me

This week, Jamie reads listener emails and opens up about the feeling of all eyes on you when you're struggling, the anxiety of the lead up, caregiving, and more. Execut

Jul 21
48 min

Chart trend

Position in the Personal Journals chart (US), last 90 days.

#1#17#32JunJulAugSep

all-time peak

days in the top 3 since Nov 2024

Chart positions

Where MeSsy with Christina Applegate & Jamie Lynn Sigler ranks today in each Apple Podcasts chart (US, Sep 24, 2026).

#19 ▼ 2 Personal Journals US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

I recently discovered this podcast a few months ago. I have many episodes to go back to ! While I don’t have MS, Ive had chronic lyme for decades and am remission from lung cancer. I appreciate the raw and real talk, connections with actual people, the guests who share their stories, and the relatability of both ladies. While none of us with diagnoses and symptoms want to identify with what they are , it is refreshing to feel Im not alone in living with chronic anything while continuing to build and live a meaningful life. Ive also listened to both books. It is strange to feel I know these ladies even through their books with millions of others but that’s what it feels like on this side- Thank you, Christina & Jamie! And miss you Christina-

Moongirl7364 · Sep 2026

I can’t believe how long it took me to find this podcast. I’m so happy I did! I also am only on the 20th episode, so I’m so happy I have so many more. I just finished both books. They were incredibly inspirational and eye opening. I can relate to both of you and I wish I could be best friends with you both! I have very similar symptoms, especially with my legs. I can relate to staying in bed. It’s my safe place. I am surrounded by amazing family and friends, but have felt so alone in my diagnosis. I thought maybe it was MS, but the diagnosis was Peripheral Neuropathy. I feel blessed beyond belief to have found you two and to have the honor and privilege of reading your books and now feeling so much support from MeSsy. Thank you! Jill- also a lifelong Palisadian

Jillali18 · Jul 2026

I don’t have a significant other, husband or boyfriend, but I do have brothers who are acting as my caregivers. This episode hit close to home because I recognize a lot of their challenges and struggles in what Cutter shared during your conversation. Jaime thanks for all the prep you did. Your questions were totally on point. You may have said it was couple’s therapy but I believe a better description is relationship strengthening. Thanks for the suggestions/advice and example of good, healthy communication.

Lisard01 · May 2026

I’ve been listening to this podcast since they started it and absolutely love their pure honesty and I’m constantly shocked at all they have to go through, it’s eye opening! Today’s episode with Jaime Lynn’s husband was just SO incredibly beautiful! He’s so honest and supportive and hearing him speak about her is just the best thing! I was teary through the whole episode, you girls always get me too. His support and love is THE MOST beautiful thing! Thank you for sharing! And Jamie Lynn, you were absolutely stunning on Grey’s Anatomy, I had forgotten about you being on and I was multitasking while watching and I heard your voice and got this warm fuzzy feeling and couldn’t figure out why, since you were a new character on the show! And then I looked up and saw YOU! Such a strong and powerful woman you played and that you actually are in real life too! Thank you for sharing your true lives with us! I’ve been a fan of you Christina for as long as I can remember, and I’m older than you, ha!

lcpeebles · Apr 2026

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