MeSsy with Christina Applegate & Jamie Lynn Sigler artwork

Personal Journals · Wishbone Production

MeSsy with Christina Applegate & Jamie Lynn Sigler

by Wishbone Production

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

Chart trend

Position in the Personal Journals chart (US), last 90 days.

#1
all-time peak
30
days in the top 3 since Nov 2024

Latest episodes

Showing 20 · updated from the feed

We Fight For Joy with Kelsey Chittick

#16 trending · Personal Journals

This week on Living With It, Jamie sits down with Kelsey Chittick to talk about losing her husband suddenly, raising two children through grief, and learning to build a l

Sep 3
53 min

There’s No Place Like Home with Annie Meyers-Shyer

This week, Jamie is joined by her longtime friend Annie Meyers-Shyer, the creator behind This Oak House. They talk about Annie’s unexpected second act, finding a new pass

Sep 1
53 min

The Power of Radical Acceptance with Jim Curtis

This week on Living With It, Jamie sits down with Jim Curtis, a transformational coach, author, and wellness leader. They discuss how to radically accept the life you hav

Aug 27
53 min

Jamie's Son Beau

This week, Jamie sits down with a very special guest: her 13-year-old son, Beau. They have an honest conversation about what it’s been like growing up with a mom who has

Aug 25
42 min

Accept, Adapt, Appreciate with Odette Annable

This week on Living With It, Jamie sits down with her friend Odette Annable. They discuss parenting a neurodivergent child, trusting your instincts, advocating for your f

Aug 20
54 min

The Courage to Slow Down

This week on MeSsy, Jamie opens up about reaching her limit and learning to make rest part of healing. She also reads listener emails about fighting to be heard by doctor

Aug 18
53 min

Finding Stillness When Life Won’t Slow Down with Bob Roth

This week on Living With It, Jamie sits down with Bob Roth, a leading Transcendental Meditation teacher and CEO of the David Lynch Foundation. They discuss what stress do

Aug 13
1 h 00 min

How Death Informs How We Live with Julie McFadden

This week, Jamie sits down with hospice nurse Julie McFadden to talk about changing the way we think about death, what she’s learned from those at the end of life, and ho

Aug 11
58 min

Trusting the Journey with Becca Tobin

This week, Jamie sits down with one of her best friends, Becca Tobin, for a conversation about infertility, pregnancy loss, surrogacy, and finding hope after years of unc

Aug 6
57 min

Try to Find the Light with Amanda Kloots

This week, Jamie sits down with Amanda Kloots for an honest conversation about finding joy alongside heartbreak. Amanda opens up about losing her husband, Nick Cordero, h

Aug 4
59 min

Look for the Signs with Kate Doerge

On this episode of Living With It, Jamie sits down with Kate Doerge to discuss finding hope after profound loss, recognizing signs from loved ones, and the five actions t

Jul 30
58 min

Hope Can Exist Alongside Fear with Myriam Sandler

This week, Jamie sits down with Mothercould creator Myriam Sandler. They discuss her recent MS diagnosis, trusting your intuition, and finding hope even when life doesn't

Jul 28
1 h 07 min

It's Okay Not to Be Okay with Amy Kurtz

On the first episode of Living With It, Jamie sits down with Amy Kurtz, a patient advocate and author. They discuss the grief of chronic illness, learning to trust yourse

Jul 23
55 min

All Eyes on Me

This week, Jamie reads listener emails and opens up about the feeling of all eyes on you when you're struggling, the anxiety of the lead up, caregiving, and more. Execut

Jul 21
48 min

Tamsen Fadal

This week, Jamie sits down with journalist, author, and menopause advocate Tamsen Fadal. They discuss the physical and emotional realities of perimenopause, why so many w

Jul 14
56 min

You Do Not Have to Become Someone Else to Heal

This week, Jamie reads listener emails and discusses the invisible weight of living with chronic illness, the courage it takes to keep showing up, and the small moments t

Jul 7
51 min

Erin Moriarty

This week, Jamie sits down with Erin Moriarty. They discuss Erin's journey with Graves' disease while starring in "The Boys," the invisible toll chronic illnesses can tak

Jun 30
1 h 02 min

Mia Calabrese

This week, Jamie is joined by Summer House’s Mia Calabrese. She opens up about her journey with grief and what’s helped her to find joy again. They also discuss the Summe

Jun 23
50 min

Choose Yourself

This week, Jamie reads emails from listeners. She also discusses mom guilt, PMS and MS, letting people know how their actions affect you, and much more.  Executive Produ

Jun 16
49 min

Our Favorite Bravo Men

This week, we are revisiting conversations with some of our favorite Bravo men - Jesse Solomon, Carl Radke, and Andy Cohen. They share moments that were challenging, help

Jun 9
1 h 03 min

Chart positions

Where MeSsy with Christina Applegate & Jamie Lynn Sigler ranks today in each Apple Podcasts chart (US, Sep 4, 2026).

#18 ▼ 1 Personal Journals US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

I’m also a mom of three kids who has been battling MS since 2000. I appreciate your honesty, even when it’s not pretty, and the empowerment you give to all in the MS community. Being a mom and having MS is not for the faint of heart but it’s also not impossible. We are capable of so much more than we give ourselves credit for.

agraves59 · Dec 2024

I needed this show so much when I found it! I am one of those annoying people you refer to that is living almost normally with MS. However, this disease reeks invisible havoc on my body and wellbeing. I can’t run anymore but I can walk. Living in this capitalist world that punishes weakness and the need to rest is a constant struggle, one that has brought me to a breaking point more than a few times. I really love what these women have to say and relate to their struggles but have also made me so grateful that I can still do so many things. I am going to do the things I love while I still can. Thanks for helping me find this perspective of gratitude.

Karebee · Dec 2024

I was sitting at my infusion center scrolling through my podcasts while I was getting one of my 6 month infusions, and I came across this wonderful podcast. I can’t begin to say how happy I am to hear these two amazing women talk about their MS issues because it helps me to know I’m not the only one struggling. It also helps that they are both so real while talking about these problems. They truly take the words out of my mouth when I’m talking about MS and the struggles that come with it.

stevenston · Dec 2024

I feel so validated listening to this podcast, I just want to scream! I’ve been living with MS for six years and it’s so helpful being able to hear these honest conversations about all the experiences that come with this condition. Thank you for opening up and sharing your stories! It’s a true source of strength!

Kellie Baldwin · Nov 2024

We strive to present a balanced view by showing a diverse range of reviews from Apple Podcasts.

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About MeSsy with Christina Applegate & Jamie Lynn Sigler on Reason.fm

Here you find the Apple Podcasts chart positions of MeSsy with Christina Applegate & Jamie Lynn Sigler, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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