Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast artwork

Medicine · Tania Dempsey, MD with Jill Brook, MA

Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast

by Tania Dempsey, MD with Jill Brook, MA

Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls. These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at ThePOTScast.com.

Latest episodes

Showing 20 · updated from the feed

Campaign against synthetic fragrances with Attorney Scott Cole

In this episode, we explore the legal and civil rights issues surrounding chemical and fragrance intolerance, including what happens when people are unable to safely acce

Sep 13
53 min

Lyme disease Q&A with Dr. Tania Dempsey

In this episode Dr. Dempsey answers listener questions about Lyme disease, sharing why it can be complex, her treatment approach at different stages, how she starts treat

Aug 15
33 min

Endometriosis with Dr. Tania Dempsey

Is endometriosis related to mast cells and MCAS in some people?  Dr. Dempsey explains why she suspects a link, how fertility, insulin resistance and pelvic congestion syn

Jul 12
49 min

GLP-1s in MCAS with Dr. Tania Dempsey

This is a not-to-be-missed episode!  Dr. Dempsey discusses the use of GLP-1 medications for MCAS, including her most recent observations and recommendations.  This is a f

May 30
41 min

Cell membrane health and why it matters for MCAS and beyond with Dr. Melanie Stein and Dr. Tania Dempsey

Dr. Melanie Stein, ND is a licensed Naturopathic Physician in Portland, Oregon and a recognized leader in Cell Membrane Therapy for the treatment of complex and chronic i

Apr 1
52 min

More cutting edge treatments (part 2) with Dr. Tania Dempsey

Dr. Dempsey is always looking for new ways to help her complex patients.  In this episode Dr. Dempsey discusses how she incorporates treatments with Methylene Blue, pepti

Mar 1
47 min

Pediatric Complex Chronic Illness & Treatment with Dr. Casey Kelley

Dr. Casey Kelley is Board Certified in family and integrative medicine, teaches on the faculty of the Northwestern Medical School, and her care is informed by her own pas

Feb 10
40 min

Neurogastroenterologist Zac Spiritos, MD, MPH with Dr. Tania Dempsey

Dr. Spiritos is double board certified in gastroenterologist and internal medicine, and specializes in IBS, gut motility, POTS and the complex conditions and symptoms tha

Jan 13
1 h 02 min

Dr. Dempsey on cutting edge treatments she is seeing help complex patients

One of the most common questions we get from listeners is about the novel treatments that Dr. Dempsey mentions, such as therapeutic plasmapheresis exchange (or apheresis)

Dec 15 2025
1 h 04 min

Dr. Eboni Cornish on root causes of brain inflammation

This is a not-to-be-missed episode for anyone interested in brain inflammation.  Dr. Eboni Cornish, M.D. is Associate Medical Director at Amen Clinics, Fellow and Treasur

Nov 17 2025
48 min

Jill Krapf on painful sex, vulvovaginal disorders and mast cells with Dr. Tania Dempsey

Dr. Jill Krapf is a Board-Certified OB/GYN who specializes in genitopelvic pain and skin conditions, is founder of the Center for Vulvovaginal Disorders and co-author of

Oct 26 2025
47 min

Dr. Greg Plotnikoff on favorite new findings, a thiamin theory and more

Dr. Greg Plotnikoff is a thought leader in dysautonomia/MCAS and complex chronic illness and in this episode he is freshly returned from giving two presentations at the D

Sep 14 2025
50 min

MCAS symptoms “down there” with Dr. Tania Dempsey

MCAS doesn't ignore the nether-regions, so in this episode, Dr. Dempsey discusses symptoms and treatments in the genitourinary and surrounding areas, including some novel

Aug 16 2025
50 min

Todd Maderis, ND on latest tests and treatments for underlying causes

Dr. Todd Maderis is a naturopathic physician in Marin, CA, who began his career in environmental medicine and now specializes in helping complex patients by searching for

Jul 7 2025
1 h 02 min

Dr. Alexis Cutchins on venous compressions, POTS, MCAS, MALS and more

This is an excellent discussion for patients and practitioners alike who are interested in the connections between MCAS, POTS, venous compression, pelvic venous disorder,

Jun 10 2025
53 min

Women’s sexual health with Dr. Anna Cabeca

Dr. Anna Cabeca started her career as a researcher and busy physician, until her own fertility issues drove her to search the world over for better solutions for women's

May 12 2025
47 min

MCAS in Developmental and Behavioral Pediatrics with Donna Kirchoff, MD, FAAP

Dr. Donna Kirchoff is an integrative developmental and behavioral pediatrician who works with children who have complex conditions, often involving MCAS, autism and other

Apr 15 2025
49 min

From Ayurveda to Apheresis with Gillian Ehrlich, DNP, ARNP

Gillian Ehrlich's NeuroVeda Clinic in Seattle treats complex patients with a wide variety of treatments including peptides, Ayurvedic medicine, diet and nutrition, imagin

Mar 11 2025
55 min

SIBO and gut health driving MCAS with Dr. Michael Ruscio

Dr. Ruscio is a thought leader, expert, clinician and researcher (and podcaster!) specializing in gut health and SIBO - small intestinal bacterial overgrowth.  In this ep

Feb 13 2025
55 min

Vibrant health starts with the heart - Master Coach Joseph Anew

Joseph Anew is now the picture of health and fitness, but as a young man he was severely injured and received a dior diagnosis. When conventional treatments failed, he mo

Dec 9 2024
1 h 05 min

Chart trend

Position in the Medicine chart (US), last 90 days.

#17
all-time peak
23
days in the top 50 since Nov 2024

Chart positions

Where Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast ranks today in each Apple Podcasts chart (US, Sep 18, 2026).

#111 ▼ 16 Medicine US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

Revolutionary information that EVERY specialty must know. My daughter has a more severe presentation of this all than I do. But, suddenly our whole life experience finally makes sense. I cannot thank you both enough. Now, digging deep to find the RIGHT protocol. It’s up to me because there is not a single mast cell specialist taking new patients in the entire state I reside. The detailed information is extraordinarily helpful.

K Car1234 · Feb 2024

I have only listened to the first episode so far, but I am just so grateful for the time and care taken by all those involved to do this podcast. My mcas journey has been long and stressful and has included a lot of medical trauma from uninformed doctors. Thank you for helping educate the medical community and everyone else.

Dr. PJ 3 · Jan 2024

This is the best source of MCAS (mast cell activation syndrome) information around. Thank you for making this free and available.

POTSy me · Dec 2023

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About Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast on Reason.fm

Here you find the Apple Podcasts chart positions of Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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