JAMA+ AI Conversations

From Aging to AI and Beyond: A Conversation With Eric Topol

In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Eric Topol, MD, move from the science of aging to how to think about AI-enabled medicine. Topol discus

ADVOCATing for Patients With Heart Failure

In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Haider Warraich, MD, sort out the prospects for AI-driven heart failure care that doesn't entail a hum

Enriching Clinical Trials With Machine Learning

In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Joseph Geraci, PhD, of Queen's University discuss using machine learning to analyze clinical trials an

From the JAMA Network: Acoustic Analysis of Primary Care Patient–Clinician Conversations to Screen for Cognitive Impairment

Interview with Joseph T. Colonel, PhD, author Acoustic Analysis of Primary Care Patient–Clinician Conversations to Screen for Cognitive Impairment. Hosted by Cynthia E. A

From the JAMA Network: AI Scribes Are Here, but Is Health Care Ready?

The rise in use and function of ambient AI scribes is arguably one of the fastest technologic changes ever seen in health care. In this episode of Healthy Dialogue, host

From Silicon Valley to the Vatican: The Expanding Debate on AI Ethics

In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Yulin Hswen, ScD, MPH, discuss Anthropic's participation in the Vatican presentation of Pope Leo XIV's

The Wizard of Oz in Medical AI

Is it enough for AI to be accurate, or are we mistaking performance for impact? Does AI change clinician behavior, improve patient decisions, or simply create a convincin

Teaching AI to Read Patient Histories

Every patient has a story, but in modern health care that story is buried across thousands of notes, lab results, and fragmented records. Nigam H. Shah, MBBS, PhD, of Sta

Designing Trustworthy Clinical AI

Join JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, for a conversation about the practical implementation of trustworthy clinical AI. Guests Emily Tat, MD, and Peter Br

AI at the Policy Table

As artificial intelligence increasingly shapes population health decisions, evidence and accuracy matter. In this episode of JAMA+ AI Conversations, Associate Editor Yuli

AI Drug Safety in Pregnancy

Why can signals that appear consistent across many studies still reflect shared bias; how do sibling comparisons help recalibrate cumulative evidence; and what AI-enabled

Understanding Disease Trajectories With AI

How might AI amplify epidemiological insight into neurodegenerative and systemic disease? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with Fang Fang, MD, PhD,

AI Chatbots and Youth Mental Health

What are the safety, evidence standards, and transparency needed for AI chatbots used in mental health contexts, particularly for young people. John Torous, MD, MBI, JAMA

Leaping Forward Into… What? An Interview With Dr Robert Wachter

Dr Robert Wachter, chair of the Department of Medicine at UC San Francisco, speaks with JAMA+ AI Editor in Chief Roy Perlis about his new book, "A Giant Leap." Their disc

AI and "Do No Harm"

In this episode, JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with David Wu, MD, PhD, and Adam Rodman, MD, MPH, about what safe clinical use of LLMs requires.

Stumbling Toward AI in the Clinic

In this episode of JAMA+ AI Conversations, Editor in Chief Roy Perlis and Associate Editor Yulin Hswen debate recent articles highlighted in JAMA+ AI, including work on p

Chatting With a Chatbot: The History of the First Clinical Chatbots, Straight From an LLM

A large language model (LLM) details the history of 2 early chatbots, ELIZA and PARRY, in conversation with JAMA+ AI Editor in Chief Roy Perlis. This podcast was recorded

Seeing Health Through the Eye and AI

Retinal images are becoming powerful windows into human health. Cecilia Lee, MD, MS, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen to explore how AI-enhanced imagi

Multiple Reasoning Models and the Future of AI Chatbots

AI chatbots have advanced rapidly, incorporating new reasoning architectures that reshape decision-making and medical education. Jonathan Chen, MD, PhD, and Ethan Goh, MD

Discussing the Latest Research in AI and Health

JAMA+ AI Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss some of the most cited AI papers in 2025 across the JAMA Network. A little bit of gen AI, som