This Week in Virology

TWiV 1373: Challenging Dengue and RIGging Flu

TWiV explains results of a dengue virus human challenge which reveals that preexisting immunity shapes viral replication and broadly protective responses, and how influen

TWiV 1372: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are cautiously elated by results of election day 2026 on the backdrop of additional measles associate

TWiV 1371: How to Bat Away Marburg Virus

TWiV discusses an outbreak of H5N1 influenza viruses in Utah farmed mink, and divergent species-specific antiviral responses in Marburg virus infected cells from reservoi

TWiV 1370: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by the continued upheaval of leadership at the CDC, recent news of H5 highly pathogeni

TWiV 1369: Florida Model Makes Measles Great Again

TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolu

TWiV 1368: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are discouraged by the continuous attack on vaccines especially the birth dose of the hepatitis B vir

TWiV 1367: Turning Off Hepatitis B Virus Without Cutting its DNA

TWiV explains a study which shows that influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primat

TWiV 1366: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebol

TWiV 1365: Andes Virus Up Close

TWiV travels to Porto, Portugal for the annual meeting of the European Society for Clinical Virology, where he speaks with Catherine and Corinne about their work on the A

TWiV 1364: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss their continuing struggle to understand the ongoing outbreak of cyclospora, decimation of US

TWiV 1363: A Cauldron of Bats

TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence ar

TWiV 1362: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections,

TWiV 1361: Ancient Viral Sword and Shield

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and t

TWiV 1360: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy’s undermining of vacc

TWiV 1359: SSPE, the Long Shadow of Measles

Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain s

TWiV 1358: Clinical Update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola o

TWiV 1357: Furin, Naturally with Paul Bieniasz

Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the vira

TWiV 1356: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed cha

TWiV 1355: Four billion years of AI training data

TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resist

TWiV 1354: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello remember Dolly Parton and her patronage of science, especially development of the COVID-19 vaccines,