This Week in Parasitism

TWiP 287: A Vaccine Against Schistosomiasis? SchistoShield Heads to Phase 2

Mumtaz Balkhi joins TWiP to discuss phase 1 and 1b trials of the schistosomiasis vaccine SchistoShield which demonstrate that it induces functional immune memory response

TWiP 286: Pinworms keep coming back! How to stop reinfection in your home

TWiP solves the case of the adult female with a 2 year old child who develops anal irritation, but the child and the husband are fine. Hosts: Vincent Racaniello, Daniel

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP reviews our current understanding of the biology of Cyclospora, the parasite currently causing a large multistate outbreak in the US traced to contaminated lettuce,

TWiP 284: It's not the pork

TWiP solves the case of the 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and presented with headaches for nearly 1 year. Host

TWiP 283: Warming up to cryptosporidiosis

TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia. Hosts: Vincent Racaniello and Christina Naula Subsc

TWiP 282: Does he live in New York?

TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous

TWiP 281: Ants under the influence

TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a gr

TWiP 280: The wriggling diagnosis

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather acti

TWiP 279: Tolling for hookworms

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hoo

TWiP 278: Trichinella from eating bear eyeballs

TWiP solves the case of the male in his 20s from Hokkaido, Japan, who developed fatigue and rash, followed by fever and myalgia 6 days later, after eating a raw bear eyeb

TWiP 277: Rif-ing on river blindness

TWiP 277: Rif-ing on river blindness April 21, 2026 TWiP reviews the global, regional, and national burden of Chagas disease, and comparison of doxycycline and rifampicin

TWiP 276: Travel history is the key

TWiP solves the case of the man in his 60s experiencing weight loss, fatigue, and loss of appetite. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Sub

TWiP 275: Novel malaria vector control

TWiP reviews the effectiveness of long-lasting spatial repellent emanators against malaria in humanitarian crisis settings in northern Nigeria, and Dengue suppression by

TWiP 274: Four tablets for bloating

TWiP solves the case of the 40 year old male who travels to India and develops intestinal bloating and diarrhea. Hosts: Vincent Racaniello, Daniel Griffin, and Christin

TWiP 273: Intestinal parasites in dogs

TWiP reviews intestinal parasites in dogs and their association with clinical manifestations of canine visceral leishmaniasis. Hosts: Vincent Racaniello, Daniel Griffin

TWiP 272: Don't look and you won't find

TWiP solves the case about the man with positive Strongyloides serology who is waiting for a kidney transplant. Hosts: Vincent Racaniello, Daniel Griffin, and Christina

TWiP 271: The silent lesion

TWiP explores female genital schistosomiasis and associated genital infections in Southern Malawi, a neglected tropical disease. Hosts: Vincent Racaniello, Daniel Griff

TWiP 270: They bake my noodle

TWiP solves the case about the man with abnormal brain MRI, and presents a new case for your solving about a man with some electrolyte issues related to his end-stage ren

TWiP 269: Peripatetic Martin Grobusch

TWiP travels to Toronto, CA for the American Society for Tropical Medicine and Hygiene conference where they meet up with Martin Grobusch to discuss his career and his wo

TWiP 268: A loyal parasite

TWiP discusses a 41-year long human infection with Schistosoma mansoni, and CRISPR screens that reveal genes essential for Cryptosporidium survival in the host intestine.