Approved artwork

Life Sciences · Alex Kesin and Matthew Pech

Approved

by Alex Kesin and Matthew Pech

Life sciences, under the hood. Deep dives into the patent filings, regulatory gauntlets, and capital-risks that shape the business of biology.

Latest episodes

Showing 5 · updated from the feed

What is Approved?

Approved tells the definitive stories behind the world's most interesting biotech ventures.  Most people learn about the industry in a fragmented, ad hoc way-- an indust

Sep 14
3 min

Blueprint Medicines: Chasing Gleevec to a $9B Allergy Drug

Blueprint Medicines was built to find the next Gleevec-style cancer drug. It ended up pivoting to allergic disease instead, and selling to Sanofi for $9B. This is the pla

Aug 4
2 h 29 min

Keytruda: How Merck's Pembrolizumab Became the Best-Selling Cancer Drug of All Time

Keytruda is Merck's $31 billion a year PD-1 inhibitor and the best-selling cancer drug of all time. In Episode 3 of Approved, Alex Kesin and Matthew Pech trace the develo

May 14
2 h 07 min

Episode #2: Geron

Listen on Spotify Listen on Apple Podcasts Listen on YouTube TABLE OF CONTENTS (00:00:00) - Introduction  (00:01:19) - Hayflick Limit  (00:08:30) - Michael West & F

Mar 13
2 h 22 min

Episode #1: Amylin Pharmaceuticals

Listen on Spotify Listen on Apple Podcasts Listen on YouTube TABLE OF CONTENTS (00:00:00) - Introduction (00:04:40) - $50 of Dried Lizard Venom (00:29:17) - Fax of

Jan 30
1 h 46 min

Chart trend

Position in the Life Sciences chart (US), last 90 days.

#13
all-time peak
53
days in the top 50 since Jul 2026

Chart positions

Where Approved ranks today in each Apple Podcasts chart (US, Sep 17, 2026).

#48 ▲ 3 Life Sciences US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

Where others interview today's CEO about tomorrow's pipeline, they examine what actually happened and why it mattered. They go back to primary sources — patents, SEC filings, clinical records — to reconstruct the origin story and the critical decisions that shaped it. Best Biotech Podcast to learn the ins and outs of the industry. Highly recommend it.

mevesavard · Apr 2026

We strive to present a balanced view by showing a diverse range of reviews from Apple Podcasts.

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About Approved on Reason.fm

Here you find the Apple Podcasts chart positions of Approved, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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