The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Latest episodes
Showing 20 · updated from the feed
Why AI Could Turn Small Law Firms Into Billion-Dollar Businesses
#30 trending · Technology
What happens when AI makes legal work cheap enough to take cases lawyers couldn't afford to touch before? Eve CEO Jay Madheswaran argues that AI won't just cut costs for
Oct 30 53 min
The Startups Rebuilding American Industry | The AD50
America’s defense, energy, manufacturing, and robotics booms are increasingly becoming one story: the rebuilding of the country’s industrial base. This year’s AD50 highli
Oct 29 50 min
Mark Cuban on Why AI Could Turn Solo Founders Into Trillionaires
Mark Cuban thinks AI could transform healthcare, but it won’t fix opaque prices and broken incentives on its own. His starting point for employers: run every benefits con
Oct 28 1 h 01 min
Reinventing School for the AI Era | Joe Liemandt, Gagan Biyani & Erik Torenberg
What should school look like if AI can help students learn dramatically faster? Alpha School founder Joe Liemandt argues the answer isn’t to fill the extra time with more
Oct 27 56 min
OpenAI: When AI Agents Use Computers Faster Than You
AI agents are approaching a point where they can use computers faster than expert humans, turning the user interface itself into a universal way for AI to interact with s
Oct 26 45 min
The New Startup Playbook | Box CEO Aaron Levie
Can a 10-person startup outperform a company with hundreds of employees? Box CEO Aaron Levie argues AI agents are giving small teams a level of leverage that simply wasn'
Oct 25 34 min
What It Takes to Win as a Founder | Ben Horowitz
What does it take to build a company when AI is changing the rules this quickly? Ben Horowitz argues that technology may make companies easier to start, but the hardest p
Oct 24 41 min
Amazon CEO Andy Jassy on the $220 Billion AI Buildout
Amazon expects to spend roughly $220 billion in CapEx in 2026, yet CEO Andy Jassy says the company is still leaving meaningful AI demand on the table.** He believes the b
Oct 23 1 h 01 min
The Frontier Ideas a16z Wants to Fund | Marc Andreessen, Ben Horowitz & Chris Dixon
a16z is expanding a16z crypto into a16z Frontier, a broader mandate to back founders building at the edges of what's possible. Chris Dixon joins Marc Andreessen, Ben Horo
Oct 22 1 h 01 min
The Missing Infrastructure for AI Agents: Documents | Reducto’s Adit Abraham
AI agents can reason over enormous amounts of information, but much of the world’s actual work is still trapped in PDFs, spreadsheets, scans, and other formats that model
Oct 21 38 min
What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal
More than 300 million people use ChatGPT for health and wellness questions each week. OpenAI’s Karan Singhal thinks that’s only the beginning: the longer-term goal is AI
Oct 20 55 min
What Happens When Al Agents Can Spend Your Money?
Why hasn't AI transformed everyday work as quickly as coding? Town CEO Jean-Denis Greze argues the bottleneck isn't intelligence, but making AI useful to people who don't
Oct 19 1 h 02 min
Why Real-World AI Is Harder Than the Benchmark | EliseAI’s Mario Martone
What changes when an AI mistake doesn’t just hurt a benchmark score, but affects someone’s housing or healthcare? EliseAI Head of Applied Research Mario Martone argues th
Oct 18 24 min
Why AI Could Finally Fix Healthcare Access | Zocdoc CEO Oliver Kharraz
Why is booking a doctor's appointment still so difficult, and can AI finally change that? Zocdoc CEO Oliver Kharraz argues that the real problem isn't finding doctors, bu
Oct 17 34 min
AI Can Write the Code. Can It Run the System? | Grepr CEO Jad Naous
a16z General Partner Martin Casado sits down with Grepr CEO Jad Naous to ask what comes after AI learns to write code: can it also debug and operate the systems that code
Oct 16 1 h 00 min
When AI Agents Start Spending Your Money | Alex Rampell & Terry Angelos
a16z General Partner Alex Rampell sits down with VGS Executive Board Member, Terry Angelos, to unpack what happens to payments when AI agents go from recommending what to
Oct 15 51 min
Can Open Models Keep Up With the AI Frontier? | Nathan Lambert
a16z Partner Lisha Li sits down with AI researcher and Trillium founder Nathan Lambert to ask how durable the gap really is between frontier AI labs and open models.
Nat
Oct 14 59 min
Can AI Break Cryptography? What the Experts Actually Think
Could AI break the cryptography protecting everything from crypto wallets and banking to private messages? Recent advances in AI-driven mathematical research have sparked
Oct 13 42 min
The Race to Recursive Self-Improving AI
a16z General Partner Martin Casado sits down with MakerMaker.AI co-founders Dhaval Adjodah and Owen He to unpack recursive self-improvement, or RSI, and separate the incr
Oct 12 33 min
Nick Bostrom: How Should We Navigate Superintelligence?
Nick Bostrom joins Theo Jaffee and Sofia Puccini on MTS to revisit the ideas about superintelligence and existential risk that he helped bring into the mainstream, now th
Oct 11 53 min
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Where The a16z Show ranks today in each Apple Podcasts chart (US, Oct 31, 2026).
A curated, balanced selection of Apple Podcasts reviews.
Consistently impactful topics. Provocative policy discussion distinguishing a health focus from disease focus where the former offers sustainable solutions.
[ lblank ] · Nov 2024
This podcast is a must-listen for its insightful discussions at the crossroads of technology, business, and culture. Steph is a super engaging host, and they have a diverse range of industry expert guests that make complex topics accessible and fascinating for all.
Rios111 · Jan 2024
Enjoy many episodes and range of topics, speakers and perspectives shared. Good mix of tech , impact and eye on future! Also enjoy hear the founders on some shows
SRam5 · Nov 2023
Excellent interview with Joon Park, thank you, your team at a16z is setting up a very important link between human behavior and generative AI, digital/interpretive behavioral modeling and other types of large language processing designs to close the gap between the vast complexity of neurobiological processes that leads to specific behavioral expressions and codifying and encapsulating that in a generative AI system, looking forward to more of those types of episodes that also address specific behavior such as violence and anger and aggression to highlight research teams around the world working on better understanding of how to intervene and treat aggressive behavior in order to create more peaceful individual and societal behavior.
Sheldon1818 · Nov 2023
A16Z often has great tech related guests and fairly good interviewers, but sometimes the audio quality is horrible. For example, the recent Balaji episode from April 22nd is unlistenable.
Alex kahn · Apr 2026
Used to be a great podcast for insights on innovation, holistic disruptive thinking, and actual innovation. After a number of departures 2 or so years ago, everything has gone sideways. Has gone from a must listen to actively being counter productive to listen to. Such a shame. And such a waste that they’ve gone so far off the rails.
StudytheWorld · Jul 2024
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