Latent Space: The AI Engineer Podcast

🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing

A few years ago, Caltech Prof. and co-founder of Accelerated Understanding, Anima Anandkumar set out to develop the first open-source weather model with AI. Talking to ex

Simulation: the new Scaling Law — Joon Sung Park, Simile AI

When we first dicsussed the Summer of Simulative AI in 2024 we knew it would be a brief summer, but it has recently come back with a vengeance with SimGym in April and no

🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

This January, four big AI × Pharma tools deals were announced at the huge JPM Pharma conference that takes over San Francisco every year. OpenAI-backed Chai Discovery (no

The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Watch the full episode on YouTube: We first covered Baseten last year when DeepSeek mania was at peak hype. Now they have raised a monster $13B round and become one of t

Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

There are roughly 100x more people who use code than who can write code. As code that “just works” becomes easier to generate, this group may be the biggest prize of all

Inside the Model Factory — Eiso Kant, Poolside AI

In recent months, the open vs closed, and US vs China discussions on model ownership and sovereign/local AI have heated up to a fever pitch. So it is very very good news

🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

Bet on information If test loss flatlines after 1.5B parameters while training loss continues to drop as you scale, that tells you that your model is limited by the amou

🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. The next AI data center? No. This is Lila Sciences‘ dream for the fu

Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

We’ve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from Databricks to Daytona to Railway and, even further back, E

🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

This episode has a fun personal twist: There’s a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind today’s episode. A certain intro

Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

We’re excited to have Databricks join us at AIEWF, among hundreds of the top companies in the AI Engineer ecosystem. LS subscribers can use their discount to get past the

Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

AI Engineer World’s Fair regular bird tix will sell out ~today! Join us next week ahead of the Late Bird price hike and get >$40,000 in sponsor credits for attending! Th

The Professor of Outputmaxxing — Anjney Midha, AMP

Last 4 days before regular tickets sell out at AI Engineer World’s Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, and Researchers in the

🔬 The Self-Driving Lab — Joseph Krause, Radical AI

On the Science pod, we’ve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since our launch is which fie

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

The new AIEWF website is live! Get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AIE WF tickets! Most

🔬Scaling Past Informal AI - Carina Hong, Axiom Math

In 2025, seven-month-old startup Axiom solved all 12 of the problems Putnam exam (scoring 8/12 in the time limit) a prestigious undergraduate math exam. The 12/12 score i

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

We’ve informally heard that Satya is a listener to LS for a couple years now, but it was still absolutely surreal to meet him and do a live pod at Build, together with ou

GitHub's plan for Agents — Kyle Daigle, GitHub

I’m excited to work with Microsoft once again as the presenting sponsors of the AI Engineer World’s Fair! We’ll streaming live from MS Build today for a special crossover

Why Video Agent models are next — Ethan He, xAI Grok Imagine

We’re announcing AIEWF speakers this week! Take the AI Engineering Survey! Today’s guest Ethan first joined us for the LS Paper Club as the lead on NVIDIA Cosmos World M

The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray

The new AIEWF website is live! CFPs close in 2 days and we will run our first New Engineer Orientation this weekend, get your tickets booked ASAP as they -will- sell out.