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Life Sciences · Dr. George Murphy

The ReProgram

by Dr. George Murphy

The ReProgram is dedicated to exploring how we can extend the healthy human lifespan through science and self-understanding. Hosted by Dr. George Murphy, each episode dives into the rapidly evolving fields of aging biology, longevity, regenerative medicine, and geroscience. From cellular rejuvenation and advanced therapeutics to lifestyle strategies that build resilience against disease, we examine what the science actually shows—and what it doesn’t. No hype. No myths. Just rigorous, evidence-based conversations about how we can reprogram our biology to live longer and healthier lives.

Latest episodes

Showing 20 · updated from the feed

Can We Slow Human Aging? What Would Count as Proof? | Dr. Nik Schork

🎬 EPISODE OVERVIEW The Longevity Consortium is mapping the biology of aging. We review the NIH-funded research aiming to delay chronic disease.The NIH-supported Longevit

Sep 28
43 min

Can Magic Mushrooms Change How We Age? The Psilocybin Scorecard

🎬 EPISODE OVERVIEW Could the compound in magic mushrooms influence how we age? Psilocybin research is producing intriguing findings, but changing brain activity, treatin

Sep 21
15 min

Ozempic Extended Mouse Lifespan. Does That Change the Longevity Scorecard?

ReProgram Episode 26: GLP-1 Drugs for Longevity 🎬 EPISODE OVERVIEW A drug millions of people already take extended median lifespan by approximately 12% in older female

Sep 14
12 min

The Hidden Dangers of Aging Blood: What You Need to Know

ReProgram Episode 25: 🩸 YOUR BLOOD MAY BE AGING BEFORE YOU ARE 🧠 Episode Overview Blood aging is often overlooked, but the hematopoietic stem cells inside your bone m

Sep 7
28 min

Start Here: The ReProgram | Longevity Science Without the Hype

Welcome to The ReProgram. Longevity science moves a lot slower than longevity marketing.The ReProgram explores the biology of aging, longevity drugs, regenerative medici

Aug 31
2 min

Can We Reprogram Aging? Epigenetics, Cell Identity & the Future of Rejuvenation | Dr. Jose Polo

🎬 EPISODE OVERVIEW Every cell in your body contains essentially the same DNA, yet a neuron behaves nothing like a skin cell. So what actually gives a cell its identity —

Aug 24
29 min

Creatine for Longevity? What the Science Actually Shows

🧠 EPISODE OVERVIEW Creatine is cheap, widely available, and backed by an unusually large body of human research. But its biology extends well beyond the gym. The creati

Aug 17
20 min

Can We Make Our Pets Live Longer? The Science of Pet Longevity

🐾 EPISODE OVERVIEW This episode asks a deceptively simple question: Can we actually help our dogs and cats live longer, healthier lives?We explore why companion animals

Aug 10
37 min

Can We Reprogram Aging Through Mitochondria? | Dr. Stefan Isaac

🧠 Episode Overview Mitochondria are known as the powerhouses of the cell—but energy production is only part of their story.In this episode of The ReProgram, Dr. George M

Aug 3
33 min

The ReProgram Scorecard: Metformin and Longevity

🧠 Episode Overview Metformin is inexpensive, widely prescribed, and supported by decades of clinical experience. It is also one of the most frequently discussed drugs in

Jul 20
15 min

Dr. Raghav Sehgal: Can We Measure How Fast You Are Aging?

🧠 Episode Overview What if your age on paper is not the number that matters most?In this episode of The ReProgram, Dr. George Murphy sits down with Dr. Raghav Sehgal at

Jul 13
27 min

Dr. Mimi Shirasu-Hiza: Can Meal Timing Slow Aging?

🧠 Episode Overview What if aging is shaped not only by what you eat, how much you exercise, or which genes you inherit — but also by when your body does things each day?

Jul 6
13 min

Dr. Rich Miller: “There Are No Biomarkers of Aging”

🧠 Episode Overview What if “biological age” as a single number is the wrong way to think about aging?In this episode of The ReProgram, Dr. George Murphy sits down with D

Jun 29
31 min

GLP-1 Agonists and Longevity: The First ReProgram Scorecard

🧠 Episode Overview Are GLP-1 agonists longevity drugs?Not weight loss drugs.Not cosmetic drugs.Not simply appetite drugs.In this episode of The ReProgram, Dr. George Mur

Jun 15
25 min

Can AI Decode Human Aging?

ReProgram Episode 14 AI and Longevity: Hype, Hope, and the Biology of Aging 🧠 Episode Overview What if your doctor could look at your bloodwork, medical history, genom

Jun 1
21 min

NAD and Aging: Did We Get the Story Wrong

ReProgram Episode 14 The NAD Myth? What the New Human Data Really Say🧠 Episode Overview In this episode of The ReProgram, Dr. George Murphy takes a critical but balan

May 18
22 min

Measuring and Modifying Biological Age: What the Science Actually Shows

ReProgram Episode 13 🧠 Episode Overview What does it actually mean to measure your biological age—and can it be changed? In this episode of The ReProgram, Dr. George Mu

May 4
44 min

The Biology of Recovery: Why Adaptation Fails in Modern Life

ReProgram Episode 12 Most people think they need to do more.Train harder. Push further. Add more stimulus.But what if the real problem isn’t effort…What if your body can

Apr 20
20 min

Muscle, Strength and The Biology of Staying Capable

In this episode of The ReProgram, Dr. George Murphy reframes skeletal muscle as far more than tissue for movement or aesthetics.Muscle is one of the body’s most powerful

Apr 6
24 min

Peptides for Longevity: What No One Tells You About Anti-Aging

In this episode—Part 3 of the Peptides 101 series—we move beyond healing and performance to examine one of the most compelling and misunderstood frontiers in modern medic

Mar 23
27 min

Chart trend

Position in the Life Sciences chart (US), last 90 days.

#26
all-time peak
3
days in the top 50 since Nov 2025

Chart positions

Where The ReProgram ranks today in each Apple Podcasts chart (US, Oct 4, 2026).

#163 NEW Life Sciences US

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