The ReProgram

Resveratrol and Longevity: What Does the Human Evidence Show?

🎬 EPISODE OVERVIEW Does resveratrol live up to the longevity hype? We examine the clinical data to see if it actually improves health markers.Research into this suppleme

Can We Reverse Aging in Humans? What the First Results Really Show

🎬 EPISODE OVERVIEW Can we reverse aging? We examine what recent clinical announcements actually prove about the state of human longevity science.Recent reports regarding

What Centenarians Reveal About Food and Aging | Dr. Paola Sebastiani

🎬 EPISODE OVERVIEW Can you actually eat like a centenarian to extend your life? We examine the evidence behind dietary habits and aging.Dr. Paola Sebastiani joins us to

Omega-3 Fish Oil: What Does the Evidence Actually Support?

🎬 EPISODE OVERVIEW Does your fish oil capsule deserve its reputation? In Episode 31, I review omega-3s for heart health, cognition, and healthy aging, then give five evi

Can We Really Measure and Reverse Aging? | Steve Horvath

🎬 EPISODE OVERVIEW Can a younger clock score translate into better health?In Episode 30, I sit down with Dr. Steve Horvath to explore epigenetic clocks, biological-age c

What Long-Lived Animals Teach Us About Aging | Dr. Steve Austad

🎬 EPISODE OVERVIEW Why do some animals live so much longer than others—and what can they teach us about healthier human aging?In Episode 29 of The ReProgram, I sit down

Can We Slow Human Aging? What Would Count as Proof? | Dr. Nik Schork

🎬 EPISODE OVERVIEW The Longevity Consortium is mapping the biology of aging. We review the NIH-funded research aiming to delay chronic disease.The NIH-supported Longevit

Can Magic Mushrooms Change How We Age? The Psilocybin Scorecard

🎬 EPISODE OVERVIEW Could the compound in magic mushrooms influence how we age? Psilocybin research is producing intriguing findings, but changing brain activity, treatin

Ozempic Extended Mouse Lifespan. Does That Change the Longevity Scorecard?

ReProgram Episode 26: GLP-1 Drugs for Longevity 🎬 EPISODE OVERVIEW A drug millions of people already take extended median lifespan by approximately 12% in older female

The Hidden Dangers of Aging Blood: What You Need to Know

ReProgram Episode 25: 🩸 YOUR BLOOD MAY BE AGING BEFORE YOU ARE 🧠 Episode Overview Blood aging is often overlooked, but the hematopoietic stem cells inside your bone m

Start Here: The ReProgram | Longevity Science Without the Hype

Welcome to The ReProgram. Longevity science moves a lot slower than longevity marketing.The ReProgram explores the biology of aging, longevity drugs, regenerative medici

Can We Reprogram Aging? Epigenetics, Cell Identity & the Future of Rejuvenation | Dr. Jose Polo

🎬 EPISODE OVERVIEW Every cell in your body contains essentially the same DNA, yet a neuron behaves nothing like a skin cell. So what actually gives a cell its identity —

Creatine for Longevity? What the Science Actually Shows

🧠 EPISODE OVERVIEW Creatine is cheap, widely available, and backed by an unusually large body of human research. But its biology extends well beyond the gym. The creati

Can We Make Our Pets Live Longer? The Science of Pet Longevity

🐾 EPISODE OVERVIEW This episode asks a deceptively simple question: Can we actually help our dogs and cats live longer, healthier lives?We explore why companion animals

Can We Reprogram Aging Through Mitochondria? | Dr. Stefan Isaac

🧠 Episode Overview Mitochondria are known as the powerhouses of the cell—but energy production is only part of their story.In this episode of The ReProgram, Dr. George M

The ReProgram Scorecard: Metformin and Longevity

🧠 Episode Overview Metformin is inexpensive, widely prescribed, and supported by decades of clinical experience. It is also one of the most frequently discussed drugs in

Dr. Raghav Sehgal: Can We Measure How Fast You Are Aging?

🧠 Episode Overview What if your age on paper is not the number that matters most?In this episode of The ReProgram, Dr. George Murphy sits down with Dr. Raghav Sehgal at

Dr. Mimi Shirasu-Hiza: Can Meal Timing Slow Aging?

🧠 Episode Overview What if aging is shaped not only by what you eat, how much you exercise, or which genes you inherit — but also by when your body does things each day?

Dr. Rich Miller: “There Are No Biomarkers of Aging”

🧠 Episode Overview What if “biological age” as a single number is the wrong way to think about aging?In this episode of The ReProgram, Dr. George Murphy sits down with D

GLP-1 Agonists and Longevity: The First ReProgram Scorecard

🧠 Episode Overview Are GLP-1 agonists longevity drugs?Not weight loss drugs.Not cosmetic drugs.Not simply appetite drugs.In this episode of The ReProgram, Dr. George Mur