Mendelspod Podcast

It’s One of the Greatest Success Stories of Molecular Medicine. Genomics Historian Kevin Davies on His Latest Book about Casgevy and Sickle Cell Disease

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com It was the heady days of the CRISPR revolution and of the gene therapy Casgevy. And when

Elias Sayour on the Cancer Vaccine Breakthrough

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com After being pursued for more than 150 years, cancer vaccines may finally be having their

What Single Cell Sequencing Revealed About Pulmonary Fibrosis with Nick Banovich, TGen

Single cell sequencing has given researchers extraordinary new maps of human biology. For Nick Banovich of TGen, the burning question is how to turn those maps into somet

The Quest to Measure Protein Function with Polly Fordyce, Stanford

Stanford physicist and bioengineer Polly Fordyce has a big vision. She’s attempting to measure protein function at the scale at which we learned to measure DNA. We can se

Doubling Down on Long Reads: New CEO of PacBio, Mark Van Oene

Mark Van Oene has just taken over as CEO of Pacific Biosciences, and Mendelspod is his first interview in the new job. He began his career as a scientist studying cystic

Serge Saxonov on What’s Next for 10x Genomics

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com 10x Genomics has been remarkably good at figuring out where biology is going next. In t

“You Cannot Discover What You Cannot Make”: Lee Cronin on Programming Chemistry

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com Those of us in biology tend to think that chemistry is rather straight forward. But toda

All of Us Comes of Age. And So Does Its Funding: Josh Denny on the Next Phase of Precision Medicine

There are very few genomics projects with the level of ambition of the NIH All of Us Research Program. The latest release includes data from more than 747,000 participant

Season Opener: Is Biology Having Its Newtonian Moment? with Rob Phillips, Caltech

Welcome to Mendelspod’s 16th season! It’s hard to believe we’ve been doing this for just over 15 years, following first and foremost the people reshaping biology and med

From the Archives: Erdinc Sezgin and the Physics of Living Cells

On Mendelspod, we’re always searching for scientists who are looking at biology in new ways. Sometimes that means a new technology. Sometimes it means asking entirely dif

From the Archives: How Cellanome Is Changing the Way We Study Cell Function with Matthew Spitzer and Pier Federico Gherardini

One of the biggest technology shifts we saw in biology over the past year came from the young company, Cellanome. Instead of relying only on static single-cell snapshots,

Agilent and Oxford Nanopore Discuss Bringing Long Reads to the Clinic with a Customer

Acute leukemia patients often wait days or even weeks for the full battery of molecular tests needed to guide treatment decisions. Dr. Parth Shah from Dartmouth believes

Liquid Biopsy for the Tumor Microenvironment: with Vince Miller and Mirna Jarosz

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com We’ve become remarkably good at reading cancer cells. Spatial biology enabled us to read

Can Liquid Biopsy Transform Chronic Disease? Hamed Amini and Soheil Damangir of Hepta

This is a free preview of a paid episode. To hear more, visit www.mendelspod.com For the past decade, liquid biopsy has largely been defined by oncology. Tumors shed DNA

The UAE’s Big Bet on Genomic Medicine with Mohamed Alameri and Albarah El-Khani

The future of genomics has arrived in Abu Dhabi. On today’s show, Dr. Mohamed Alameri of the UAE Department of Health and Albarah El-Khani of M42 describe one of the mos

Ryan Flynn of Harvard on Non-Coding RNA

On today’s show, Dr. Ryan Flynn of Harvard Medical School and Boston Children’s Hospital takes us into a newly emerging layer of biology: the architecture of the cell sur

Gary Schroth on Connecting Cellular Behavior to the Transcriptome

For decades, biology has been driven by the powerful notion that if we could sequence enough genomes, transcriptomes, epigenomes, then we could finally explain the cell.

Two-Thirds of High-Risk Breast Cancer Patients May Avoid Chemotherapy According to Veracyte Data Presented at ASCO

Today on the show, we’re discussing a new study just presented at ASCO 2026 that could change how chemotherapy decisions are made for a large group of breast cancer patie

Building the Diagnostic Layer of Modern Cancer Care with Rita Shaknovich and Karina Kulangara of Agilent

For years, precision oncology has largely been discussed through the lens of breakthrough drugs. But there’s another story running underneath modern cancer care: the quie

Mapping the Multi-Omic Era with Eric Green of Illumina

Dr. Eric Green returns to Mendelspod in a new role: Chief Medical Officer of Illumina. After more than three decades at the National Human Genome Research Institute, wher