CrownCast

New Approach Methodologies in Oncology: From Concept to Use

In this CrownCast episode, host Michelle Dawn Mooney speaks with Graham Marsh, Director of the NAMs Developer Coalition at the Critical Path Institute, and Ludovic Bourré

Syngeneic vs. Humanized Models: How to Choose the Right Model for Immuno-Oncology Research

Choosing the right preclinical immuno-oncology model makes or breaks your development decisions, but navigating the options is rarely simple. In this CrownCast episode,

Top Cancer Research Trends and Innovations Identified by Experts

At AACR 2026, one message became clear: oncology drug development is entering a new era defined by smarter decision-making, integrated platforms, and increasingly precise

Mastering Radiopharmaceutical Development - Preclinical Model Selection for Clinical Success

What if the next breakthrough in cancer treatment isn't a pill or infusion, but a precisely targeted radioactive payload that hunts down tumor cells like a guided missile

Beyond Efficacy: Why DMPK and Toxicology Matter Earlier Than You Think

When people hear Crown Bioscience, they often think of world-class in vivo oncology models - and for good reason. But behind every successful oncology program is somethin

ADC Development Revolution - Leveraging Translational Models for Next-Generation Cancer Therapeutics

The Radiopharmaceutical Revolution Driving Precision in Treatment

Transforming Cancer Drug Development in the UK: Perspectives and Breakthroughs

Across the global oncology drug discovery landscape, the UK stands at the forefront. In this CrownCast episode, Rajendra Kumari, Executive Director of Integrated Solution

The Future of Drug Development: How Organoids Are Leading the Charge

As the landscape of drug discovery evolves, breakthrough technologies like organoids are gaining traction for their potential to revolutionize how new treatments are deve

Beyond Animal Testing: The FDA Modernization Act and the Future of Drug Discovery

What if the biggest barrier to faster, safer drug development isn't a lack of technology, but a decades-old reliance on the wrong models? In this episode of CrownCast, h

The Power and Potential of Biomarkers

Oncology continues to be a rapidly changing field with scientific discoveries transforming patient treatment and care. As it stands today, advancements in biomarkers are

Pioneering Strategies to Unlocking the Potential of KRAS

In the dynamic field of oncology research, KRAS has long been a formidable opponent. Originally deemed undruggable, recent breakthroughs have now positioned KRAS as a bea

Inside Oncology Drug Development: Overcoming Resistance with Science

In the last two decades, oncology has undergone a transformation with over 300 new cancer therapies approved by the FDA—many offering novel mechanisms of action. Despite

Exploring Artificial Intelligence in Drug Discovery

Artificial intelligence is rapidly reshaping the drug discovery process, moving from augmenting research to actively driving innovation. As biotech companies face soaring

Navigating Challenges: Immune Cells vs. Cancer Cells

In the ever-evolving world of cancer treatment, immuno-oncology (IO) continues to stand at the forefront of innovation. With recent FDA approvals for TIL therapies and bi

Beyond the Lab: The Evolving Role of CROs

Are you ready to understand the seismic shifts in the CRO (Contract Research Organization) industry? Join Johnny McMichael, VP of Client Experience and Enablement at Crow

The Competitive Edge: How CROs Stay Ahead in Drug Discovery