We're not getting any younger... yet. Aging and longevity science from the Buck Institute.

Q&A with Eric and Brianna

In the final episode of season 3 we answer your biggest aging questions, from whether there is a single root cause of aging to why different organs fail in different ways

Brad Younggren: Filtering Out Aging

What if removing and replacing part of your blood could turn back some of the measurable signs of aging? Brianna Stubbs talks with Dr. Brad Younggren — emergency physicia

Hanadie Yousef: Cracking the Secretome Code

In this episode, Buck scientist Brianna Stubbs joins Hanadie Yousef, Co-Founder of Juvena Therapeutics, to discuss the cutting-edge of longevity science. Dr. Yousef share

Cynthia Kenyon: Switching on Resilience

Eric Verdin sits down with Dr. Cynthia Kenyon, a true pioneer in the field of geroscience and the Vice President of Aging Research at Calico. Dr. Kenyon recounts the revo

Ana Maria Cuervo: Cellular Recycling

What if the secret to a longer, healthier life isn’t found in a new supplement or a complex medical procedure, but in your cells' own innate ability to "take out the

Jamie Justice: The New Metrics of Functional Aging

XPRIZE Healthspan Executive Director Jamie Justice joins Brianna Stubbs to discuss the $101 million race to restore 10 years of muscle, cognitive, and immune function wit

Tony Wyss-Coray: Rejuvenating the Brain

In this episode, Eric Verdin, CEO of the Buck Institute, and Stanford University’s Dr. Tony Wyss-Coray discuss the groundbreaking science of brain rejuvenation through he

George Church: Rewriting The Rules of Aging

What if aging is less a fate and more an engineering challenge? We sit down with George Church to unpack a future where gene therapy, cellular reprogramming, and AI-drive

Season 3 Trailer

We're back! Meet our new hosts Eric Verdin, CEO of the Buck Institute, and Brianna Stubbs, Director of Translational Science at the Buck. We're excited to bring

Nathan Price: Scientific Wellness and AI at the Forefront

What do we really want from our healthcare system, and how can AI help us get it sooner? In our final episode of season two, Gordon talks with visionary systems biology e

Luigi Ferrucci: Resilience as Medicine

Few people have as much experience with patient care and long-term research as the celebrated geriatrician and epidemiologist Luigi Ferrucci. Listen in as he speaks with

Andrea Maier: From Potential to Practice

The movement to integrate longevity treatments into clinical care is making strides. How can we ensure they are evidence-based, accessible, and personalized? World-renown

Daniel Belsky: Measuring the Pace of Aging

Our chronological age doesn’t tell us much about how well our bodies are aging, but scientists have developed many ways to measure changes at the cellular and molecular l

Kristen Fortney: Finding Targets for Aging Interventions

Of all the biochemical changes that occur with aging, what really matters? How can we use the incredible amount of health data available today to discover the best target

Valter Longo: Fasting for Health and Longevity

What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at the cellular level by following a fasting-mimicking die

Satchin Panda: The Age of Circadian Disruption

Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find that it influences everything from metabolism to mental h

Laura Carstensen: The Purpose and Promise of Longer Lives

What is the goal of living longer? It’s not simply to celebrate a number, but to do something meaningful with that time. Renowned Stanford psychologist Laura Carstensen s

Season Two Coming Soon!

We're back! In season one, we investigated the biology of aging in many different organisms to learn why and how we age. This season we'll take a close look at

Between the lines: Mobilizing the immune system

Gordon and Stella revisit key concepts from the conversation with Arne Akbar, such as using sestrins to modulate T-cells and telomeres. Looking back over the course of se

Arne Akbar: Immunity and Beyond

What role does the immune system play in aging? How do senescent cells evade it and promote inflammation? And what does it reveal about developing effective interventions