NEJM AI Grand Rounds

Beyond the Hype: Dr. Xiao Liu on Evaluating Medical AI

The promise of medical AI is not simply better performance — it is better care grounded in evidence patients and clinicians can trust. Dr. Xiao Liu, a clinician and medic

Dr. Suchi Saria on Building AI That Changes Care

A patient can deteriorate while the warning signs remain buried in a noisy electronic record. Dr. Suchi Saria, Founder and CEO of Bayesian Health and a faculty member at

Weave’s Brandon Rice on Rebuilding Drug Regulation with AI

Brandon Rice believes that improving health care sometimes means improving the systems behind it. Through his work at Weave, he focuses on modernizing the regulatory infr

OpenAI’s Karan Singal on HealthBench and the Future of Medical AI

Medical expertise has always been scarce. Dr. Karan Singal believes AI can help change that. Drawing on his work at OpenAI and earlier efforts behind Med‑PaLM, he discuss

The OpenEvidence Episode: Dr. Travis Zack on the Future of Clinical Evidence

Dr. Travis Zack, Chief Medical Officer of OpenEvidence, takes us behind the scenes of the start and growth of the company, and brings a clinician’s perspective to one of

Doctronic’s Autonomous AI with Dr. Byron Crowe

Doctronic CMO Dr. Byron Crowe describes how administrative complexity can interfere with timely, effective treatment, and how AI may help address those challenges. Crowe

AI’s Next Frontier with Dr. Kyunghyun Cho

Dr. Kyunghyun Cho is a leading AI researcher best known for co-authoring a landmark 2014 paper that introduced neural machine translation. In this episode, he discusses h

Epic’s Approach to AI with Seth Hain

Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain describes how Epic is building foundation models that respect institutional autonomy,

Bridging AI and Biology to Tackle Medicine’s Hardest Problems with Dr. Marinka Zitnik

For Dr. Marinka Zitnik, the promise of AI in medicine begins with acknowledging the scale of the problem. Most patients with rare diseases have no approved treatments, an

What Values are in AI? A Conversation with Dr. Zak Kohane

For Dr. Zak Kohane, this year’s advances in AI weren’t abstract. They were personal, practical, and deeply tied to care. After decades studying clinical data and diagnost

From Hindsight Bias to Machine Bias: Dr. Laura Zwaan on Learning from Mistakes

As a cognitive psychologist, Dr. Laura Zwaan studies how humans make—and learn from—mistakes. In this episode of NEJM AI Grand Rounds, she brings that lens to AI, showing

Medicine, Machines, and Magic: Dr. Jonathan Chen on Medical AI

In this episode, Dr. Jonathan Chen joins the hosts to discuss his path from teenage programmer to Stanford physician-informatician and why machine learning has both thril

From Clinician to Chief Health AI Officer: A Conversation with Dr. Karandeep Singh

Dr. Karandeep Singh brings two worlds together: programming and medicine. In this conversation, he explains how early experiments with code led him to biomedical informat

Radiologist Turned CEO: Dr. Jeremy Friese on AI for Prior Authorization

Dr. Jeremy Friese knows medicine from both sides. A practicing radiologist and technology executive, he’s seen firsthand how administrative burden undermines care. In thi

Can AI Accelerate Science? Dr. Andy Beam on AI’s Next Frontier

Dr. Andy Beam has trained models, mentored scientists, and used data to quantify the value of treatments. In this episode of NEJM AI Grand Rounds, Raj Manrai turns the ta

Google’s Efforts to Build Patient-Facing AI: A Conversation with Drs. Alan Karthikesalingam and Anil Palepu

In this episode of NEJM AI Grand Rounds, guests Drs. Alan Karthikesalingam and Anil Palepu of Google walk co-hosts Raj Manrai and Andy Beam through the making and evaluat

Rewriting the Clinical Playbook: Dr. Shiv Rao on Scaling Empathy with AI

Dr. Shiv Rao, cardiologist and CEO of Abridge, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds for an inspiring conversation at the intersection of medicine,

Pixels to Protocols: Building the AI Future of Pathology with Dr. Faisal Mahmood

Dr. Faisal Mahmood, Associate Professor of Pathology at Brigham and Women’s Hospital and Harvard Medical School, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rou

From Bedside to Boardroom: How AI, Multi-Omics, and New Business Models Are Shaping the Biomedical Frontier with Morgan Cheatham

Morgan Cheatham joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolving landscape of artificial intelligence in health care, from its role in

From Clinical Notes to GPT-4: Dr. Emily Alsentzer on Natural Language Processing in Medicine

Dr. Emily Alsentzer joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolution of natural language processing (NLP) in medicine. A Stanford fac