How God Works: The Science Behind Spirituality artwork

Philosophy · PRX

How God Works: The Science Behind Spirituality

by PRX

While religion and science often seem at odds, there’s one thing they can agree on: people who take part in spiritual practices tend to live longer, healthier, and happier lives. The big question is: Why? In How God Works, professor Dave DeSteno takes us on a journey to find out how spirituality impacts our minds and bodies, as well as the world in which we live. He speaks to leading scientists and philosophers, religious thinkers, and thought leaders to explore what we can learn from the world’s faith traditions to help us meet some of life’s biggest challenges. Along the way, he’ll look at how we can adapt and use spiritual practices in our own lives, whatever our beliefs, including none at all. It’s by working across the boundaries that usually divide us – science versus religion, one faith versus another – that we’ll find new ways to make life better for everyone.

Latest episodes

Showing 20 · updated from the feed

Season 11 Trailer

Join us for Season 11 of How God Works, starting next week!

Sep 13
3 min

HGW Presents: Oh God Now What

How God Works will be back with all new episodes in September. In the meantime, we're excited to feature an episode from our friends at Oh God Now What, hosted by Niala B

Aug 23
45 min

Bonus Episode: God, Code, and Consciousness (Aspen Ideas)

As humans increasingly turn to AI for moral guidance and answers to life’s biggest questions, the lines between technology and religion are blurring—even leading some in

Aug 2
45 min

Aliens and Spirituality (Encore Presentation)

Religion is often about powerful beings coming down from the skies and humans yearning to go up to join them. Does that mean we can swap aliens in for God? More and more

Jul 12
34 min

Searching for Signs

Throughout history, humans have searched for signs and symbols to help them navigate uncertainty. From ancient Chinese divination texts and Greek oracles to astrology, ta

Jun 21
44 min

Humor and Judaism: A Conversation with Robby Hoffman

According to a 2020 Pew Research Center survey, more American Jews cite having a sense of humor as important to their Jewish identity than things like keeping kosher and

Jun 7
37 min

Rethinking Sin… Again

We’ve all done things we’re not proud of. But why do some people seem to struggle so much more than others when it comes to avoiding harmful behavior? And what does it me

May 24
1 h 02 min

Deus Ex Machina

We’ve always assumed that if there IS a God, that God made us. But what if it ends up being the other way around… and we’re already further along than we think? Artificia

May 10
58 min

Doubt (Part II)

Uncertainty about faith can be anxiety provoking and even cause people to leave religion altogether. But that's not the way it works in all traditions. In fact, some are

Apr 26
45 min

Doubt (Part I)

Religion can help provide answers to many questions in life -  big and small.  And in doing so, give a sense of security and understanding of the world and our place in i

Apr 12
38 min

What Women Want

In conversations about women’s rights, religion and feminism are often cast as incompatible. But religious women tend to see it differently.  In this episode, we’ll expl

Mar 29
42 min

DIY Spirituality?

About 70% of all Americans consider themselves spiritual in some way, whether it be a belief in the soul, spirits or just the idea that something's going on beyond the na

Mar 15
31 min

Season 10 Trailer

Join us for Season 10 of How God Works, starting next week!

Mar 8
2 min

Uniter or Divider? Explore Religion in Modern America. A How God Works Live Event (From the Archive)

We’ll be back on March 15 with an all-new season of How God Works! In the meantime, we’re excited to share one of our favorite episodes — our very first live event. If y

Feb 22
1 h 22 min

The Spiritual (and Political) Crisis in the US (From the Archive)

A brand-new season of How God Works returns March 15! In the meantime, we’re revisiting a powerful episode from our archive that feels particularly relevant today.  Ange

Feb 8
36 min

Mattering

Feeling that our life is meaningful - that we add value to the world and are valued by the people around us, isn’t just a good feeling, it's a fundamentally necessary one

Jan 25
34 min

Rethinking Sin (From the Archive)

For many people, the word “sin” is associated with harsh judgment and shame. Or, it’s used to talk about guilty pleasures like consuming decadent desserts... But is this

Jan 11
38 min

The End of the World As We Know It

These days, it feels like the end of the world is always just around the corner. From RaptureTok to climate doom and geopolitical upheaval, someone always seems to be pre

Dec 28 2025
39 min

Dream Yoga

 We spend about a third of our lives sleeping and yet the question of why we sleep and dream has remained a mystery for much of human existence. But recently scientists h

Dec 14 2025
39 min

Shamanism

When life feels uncertain, who do you turn to? Across cultures and throughout history, many of us have looked to people who seemed to have a special set of abilities and

Nov 30 2025
40 min

Chart trend

Position in the Philosophy chart (US), last 90 days.

#8
all-time peak
7
days in the top 10 since Nov 2024

Chart positions

Where How God Works: The Science Behind Spirituality ranks today in each Apple Podcasts chart (US, Sep 20, 2026).

#66 ▼ 9 Philosophy US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

Finally - Voices of reason discussing fascinating topics of faith through a scientific lens. No judgement & no preaching.

NeneNonis · Feb 2025

Excellent episode, as a Cherokee myself, I love that the anthropologist brought Cherokee stories to illustrate points.

Trackerdoc · May 2024

I grew up Pentecostal but I distanced myself from practicing religion over the years. I find many of the episodes spark my curiosity about faith and spirituality.

Passenger 2025 · Jul 2025

I have enjoyed all of the episodes since the beginning of this podcast. Today’s “God is green” episode was so lovely and enriching thatI feel compelled to review it. 5 stars! Thank you for doing this work.

nickname4happylisten · Apr 2023

We strive to present a balanced view by showing a diverse range of reviews from Apple Podcasts.

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Here you find the Apple Podcasts chart positions of How God Works: The Science Behind Spirituality, its latest episodes to listen to directly, and reviews from listeners. Rankings are updated daily for the United States.

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