Podovirus artwork

Life Sciences · Jessica Sacher and Joseph Campbell

Podovirus

by Jessica Sacher and Joseph Campbell

Phages (bacteriophages) are viruses that kill bacteria with sniper-like precision. They can be incredibly useful for treating life-threatening infections ('phage therapy'), and can help us reduce our dependence on antibiotics. They've been known for 100 years... so WHY do we still not see them on the shelves? Jessica Sacher, PhD (Staff Scientist at Stanford and cofounder of Phage Directory) and Joseph Campbell, PhD (former NIAID program officer) talk to phage therapy practitioners, researchers and entrepreneurs to understand one question: why don't we have phage therapy yet?

Latest episodes

Showing 18 · updated from the feed

Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

Rebekah Dedrick shares her background in phage research and her transition to the Cystic Fibrosis (CF) Foundation. She explains how her work with mycobacteriophages inter

Aug 23
38 min

Cell-free synthesis for the clinic: How Invitris is building a phage printer

What if you could build biology in a tube, no cells required? Invitris is a Munich-based cell-free synthesis company starting with bacteriophages. Kilian Vogele, co-found

Jun 30
53 min

Why phage companies aren’t raising $400M rounds… yet | Paul Garofolo

“The thing everybody thinks is a tailwind for our space — the low financial barrier to get into a clinical trial — is actually one of the largest headwinds.” Paul has sp

Apr 21
1 h 02 min

Chip Schooley & Graham Hatfull: the state of phage therapy (& what HIV can teach us)

Chip Schooley (UC San Diego, IPATH) and Graham Hatfull (University of Pittsburgh) join us to discuss why phage therapy needs biologists and clinicians collaborating — and

Apr 3
1 h 06 min

How to run a phage therapy center from your academic lab

What does it take to build a phage therapy program from nothing — and keep your research lab running at the same time? In this episode, Joe and I sat down with Dr. Daria

Mar 3
54 min

AI-generated phages that work: ChatGPT for phage biologists?

Can AI design living organisms from scratch? Samuel King and Claudia Driscoll from the Arc Institute used genome language models to generate functional phages—and 16 of t

Nov 13 2025
1 h 03 min

How to get successful outcomes with phage therapy: Saima Aslam, MD, MS

"When I first started, I was treating anything and everything in terms of ‘this is highly drug resistant and it's failed’. But I think I have a clearer idea now, at least

Aug 15 2025
54 min

Dr. Marisa Azad, MD, PhD: Behind Canada's first prosthetic joint treatment with phage therapy

"It's unacceptable to just tell this poor patient, there's nothing I can do to help you... That's when I thought, okay, well, what about kind of pushing the boundaries a

Jun 27 2025
48 min

How to navigate regulatory limbo: a Canadian phage therapy CEO's playbook

"Phages are not drugs. Every time they say, 'Did you go through regulatory?' I say, 'I can do regulatory, but I'm not a drug.' There's 145 components of the regulatory re

Jun 2 2025
59 min

Why can't patients access phage therapy? Does FDA need to change, or do patients just need a voice?

"This feels just like the early days of the HIV crisis. People are dying, you're not hearing about it. We need a group like ACT UP to bring this to the public. We're not

May 9 2025
1 h 12 min

Finally, phase 2 data! Inside BiomX's successful phage therapy trial with CEO Jonathan Solomon

"Finally, finally we have Phase 2 data. We put a dent in the theory that phage therapy doesn't work. Maybe it does work. Maybe it's worth taking a risk." Jonathan Solomo

May 2 2025
58 min

Does every scientist need an AI co-scientist? How two professors solved a years-long viral mystery

"I was so biased. I knew too much and that's why we couldn't see the obvious answer that was right in front of us for years." In this episode of the Podovirus Podcast, w

Apr 9 2025
1 h 09 min

What's the business case for phage therapy?

“Getting our foot through the door to any VC... As soon as they hear we're infectious disease, their eyes kind of get big. And then they hear we're antibacterial, their e

Feb 21 2025
51 min

How to bring phages to market: Intralytix's food-to-pharma strategy

"Somebody's father, friend, husband just passed away in the most developed country in the world... from a simple infection that probably could have been treated in Georgi

Dec 19 2024
59 min

Gina Suh, MD: What it's really like to treat patients with phage therapy

What's it like to be a doctor treating patients with phage therapy in the US today? Dr. Gina Suh, Mayo Clinic infectious disease physician, tells us: - How she establis

Nov 8 2024
1 h 12 min

Jesus Fernandez-Rodriguez: How Eligo Bioscience edits gut bacteria with phages

Welcome to the Podovirus podcast, episode 3! In this episode, I talk with Jesus Fernandez-Rodriguez from Eligo Bioscience, a Paris-based biotech company pioneering microb

Sep 20 2024
57 min

Getting phage research funded — Joe Campbell reflects on a career at NIAID

Welcome to the Podovirus podcast, episode 2! In this episode, Jessica talks with Dr. Joe Campbell, who recently retired as a program officer at the National Institute o

Aug 8 2024
46 min

Why all phage researchers need to be in Australia this July

This is a very special week. We’re launching the first episode of our Podovirus podcast! We started this on a whim (I wanted to explore this format, since I love talking

May 3 2024
36 min

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Position in the Life Sciences chart (US), last 90 days.

#53
all-time peak
18
days in the top 100 since Mar 2025

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Where Podovirus ranks today in each Apple Podcasts chart (US, Sep 29, 2026).

#183 ▼ 35 Life Sciences US

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