Ion Genomics Podcast

What is Grail’s Galleri If It Can’t Be Called ‘Early?’ With Alex Dickinson

Grail’s Galleri blood-based cancer detection test appears headed towards approval by the FDA after it passed a trio of votes from an advisory committee Sept. 23. However,

Illumina’s China FOMO, with BridgeCross Bio’s Matt Marlowe

Episode 13 China’s burgeoning biotech and genomics markets make for the ultimate compare and contrast.  Like the US, it has regional hotspots, intense competition, and

How Well Do AI Models Understand Wet Lab Work? With Benchling’s Nicholas Larus-Stone

Nicholas Larus-Stone is Benchling’s Head of AI and coauthor of a new benchmarking study putting large language models (LLMs) like Claude and ChatGPT to work redesigning w

Mitochondria Are NOT Just the Powerhouse of the Cell, with Gordon Freedman

Gordon Freedman and I both developed an interest in mitochondria due to our love of cycling and to understand the limits of performance. Whereas I sought to find a racer’

How Technology and Trust Help Fight Epidemics, with Journalist Will Herkewitz

How are people fighting ongoing epidemics using genomics-based technologies such as PCR diagnostics and mRNA vaccines in a world where funding from the US and other rich

How to Wiretap a Billion Cells, with Dino Di Carlo

What happens when scientists come together and realize they didn’t have the data to back up their assumptions? Dino Di Carlo, my guest on this week’s Ion Genomics podcas

AI Agents are Coming for the Lab, With Tahoe Bio CSO Johnny Yu

My guest this week, Johnny Yu, has seen firsthand how the new code-writing capabilities of LLMs has widened horizons for the use of AI in biology. Tahoe Bio, a company he

Maximal Cancer Diagnostics with Sid Sijbrandij and Jacob Stern

In 2024, Sid Sijbrandij got the news that no cancer patient wants to hear: his tumor was back and his doctors told him they had nothing left to offer.  Sid, a tech entre

Protein Sequencing-by-Subtraction with Pumpkinseed Cofounder/CEO Jen Dionne

“We right now are developing our technology to be able very soon to sequence roughly hundred-length proteins that are on each of those sensors within a 24-hour period. Yo

Q1 Company News Roundup with Wall Street Analyst Kyle Mikson

What kind of market share can Illumina expect when it launches its own MRD kits and is it worth the risk of annoying customers that also offer those tests?  Why did liqu

Spatial Perturb-seq, so hot right now! With Alexander Nevue

“It's one extra step ahead of a single cell RNA-seq workflow where we can get all the information that we can get from standard Perturb-seq, but we also know the spatial

Remembering Craig Venter With Jamie Shreeve, Author of 'The Genome War'

Craig Venter, the renegade scientist who tried to beat the publicly-funded Human Genome Project with a private company — and nearly succeeded — died last week at 79. My

AI Virtual Cell Pioneer Christina Theodoris

Do AI models in biology have to get bigger to get better? And what can you do with more training, more computing power, and more outputs?  Joining me this week to talk a

First podcast! With 10x Genomics CEO Serge Saxonov

Earlier this week I spoke with 10x Genomics CEO and Cofounder Serge Saxonov at the AACR meeting, where 10x launched Atera, its new instrument for spatial biology. In addi