The Hilarious World of Depression artwork

Comedy Interviews · American Public Media

The Hilarious World of Depression

by American Public Media

The groundbreaking, award-winning mental health podcast is under new ownership after six years ago. Old ownership, really, since it's now run by original host John Moe.  Join John for new and classic content for frank, moving, and, yes, funny conversations with important artists who have dealt with depression and other mental health conditions. Maria Bamford, Paul F. Tompkins, Andy Richter, Open Mike Eagle, Daryl DMC McDaniels, Gary Gulman, and more.  The Hilarious World of Depression is not medical treatment and should not be seen as a substitute for therapy or medication. But it is a chance to feel less alone. The Hilarious World of Depression (THWoD) was co-created by American Public Media with support from Health Partners. 

Chart trend

Position in the Comedy Interviews chart (US), last 90 days.

#36
all-time peak
6
days in the top 50 since Nov 2024

Latest episodes

Showing 20 · updated from the feed

Welcome Back to The Hilarious World of Depression. Yes, It's a New Episode. In 2026.

After six years, The Hilarious World of Depression is back and under new ownership. John Moe, host of the program during it's initial run, has acquired the show and steps

Aug 19
19 min

Introducing Depresh Mode with John Moe: Joel Kim Booster Is In A Pit

It's tempting to try to look for a reason why Joel Kim Booster, ordinarily a very funny and engaging person, feels dead inside, trapped in a persistent depressive state.

Aug 4 2021
51 min

Movies That Get Depression Right

It’s easy for movies to get depression wrong, portraying a clinical disorder as equivalent to just being bummed out and, in the case of romantic comedies, curable with a

May 25 2020
45 min

Steven Page Camouflages Songs About Depression

As co-founder and co-frontman for the band Barenaked Ladies, Steven Page belted out a lot of up-tempo pop hits. But if you look at the lyrics to songs like "One Week" or

May 18 2020
45 min

Mike Birbiglia Faces His Darkest Fears and Puts Them On Stage

Monologist and comedian Mike Birbiglia has always had a mile-long dark streak. Even if he’s never been diagnosed with clinical depression, he’s recognized his own lack of

May 11 2020
41 min

Free Chapters of The Hilarious World of Depression: The Book: The Audiobook

To celebrate the release of our book we are excited to offer you a sneak preview of the audio version, read by author and THWoD host John Moe. Hear how he started to unlo

May 4 2020
42 min

Emmy Blotnick Once Ate a Whole Head of Cabbage. Alone. In Silence.

Standup comedian and writer Emmy Blotnick is a rising star in the comedy world. But along the path to success, she’s had to navigate a depression that manifested in some

Apr 27 2020
47 min

Lulu Miller Treats Her Depression With Fish Research, Finds Fish Don’t Exist

Public radio and podcast audiences have been listening to Lulu Miller’s storytelling for years on Radiolab and on Invisibilia, a show she co-founded. Her work is generall

Apr 20 2020
47 min

Dave Holmes Puts the ADHD in Dave Holmes

Some people don’t have short job titles. Dave Holmes is, among other things, a writer, MTV VJ (despite losing the contest that landed him the job), TV host, actor, and ev

Apr 13 2020
42 min

Call A Friend, Find Out How They’re Doing

During this long stretch of just staying home, we decided to reach out to some friends of THWoD, hear their voices, and find out how they're holding up. Writer Ana Marie

Apr 6 2020
33 min

Lori Gottlieb Has Seen All Possible Sides of Therapy

Having experienced therapy as a patient, a student, and an actual therapist, Lori Gottlieb has a lot of insight into what therapy is, what it isn't, and how to get the mo

Mar 30 2020
50 min

Jameela Jamil Has an Ambitious Goal: To Feel Things


She was one of the stars of NBC’s The Good Place, a tv and radio host in England, and she’s created a popular movement aimed at celebrating body positivity, all within th

Mar 23 2020
45 min

A Message From Inside John’s Closet. I Mean Office.

Hi, it’s John, and I’m sending you this recording from my makeshift office about what’s going on for us THWoD-balls during COVID-19, and ideas about how to get through it

Mar 18 2020
15 min

Theo Fleury: Trauma, stardom, and a downward spiral on the latest Tremendous Upside

Theo Fleury hit the ice at age five. He was a hockey phenom at 14, a Stanley Cup champion at 20 and an Olympic gold medalist at 33. He was also keeping a terrible secret.

Jan 27 2020
30 min

THWoD Special: Tremendous Upside with Chamique Holdsclaw and Metta World Peace

A special episode of our new sister program from the makers of THWoD. Tremendous Upside is a bit like THWoD, but instead of John Moe talking to artists, host and basketba

Jan 13 2020
31 min

Introducing Tremendous Upside

We are delighted to announce a brand new show coming your way from the THWoD team. Tremendous Upside is a series of interviews with athletes who have been at the top of t

Dec 16 2019
7 min

Depression’s Eleven Big Lies EXPOSED!

It's helpful to know that depression lies to you, that it presents the world in a way that is false just to mess you up. It's even more helpful to know exactly what whopp

Dec 9 2019
48 min

Darryl ”DMC” McDaniels Finds Therapy More Helpful Than Olde English 800

Run-DMC was about as successful as recording artists could be. Packed concerts, multi-platinum selling albums, MTV, fame, fortune, the whole thing. But Darryl McDaniels,

Nov 18 2019
46 min

Mark Duplass Has Two Speeds: Go and Crash

Filmmaker and actor Mark Duplass has been prolific over the course of his career. Along with his brother and creative partner, Jay Duplass, he's made films such as "The P

Nov 11 2019
49 min

Angelina Spicer Wants to Say Things Out Loud About Postpartum Depression

There's a lot of information being thrown at parents when a baby is on the way: how to make a birth plan, what kind of car seat to get, what shots the baby will need, and

Nov 4 2019
44 min

Chart positions

Where The Hilarious World of Depression ranks today in each Apple Podcasts chart (US, Sep 12, 2026).

#67 ▼ 10 Comedy Interviews US

What listeners say

A curated, balanced selection of Apple Podcasts reviews.

The original run of the show helped me keep my head above water during some of the darkest times of my life. It was beyond valuable in helping me feel less alone and for giving me perspective on many of the challenges my severe depression presented. For me, laughter truly is the best medicine. (Especially since I have a tendency to take my self too seriously.)😄 Life is more manageable for me presently but I’m excited to see/hear what this next chapter of the show has to offer. Here’s to the consummate host, John Moe! Thanks for being so caring and considerate with a topic that is quite sensitive for many of us. Keep up the good work! 👍

Zillanis · Aug 2026

I have listened to all of these episodes over and over and love them more every time. My only critique is that I wish it was still running. This is such an important topic, and such an ingenious way of presenting it

bassoonistbk · May 2025

I recommend starting with the DMC episode. This podcast has something for everyone. Hilarious, insightful, and hopeful.

Billy Hammer · Jul 2022

I searched for a podcast on depression when my husband hit a scary low in depression. Not only do I feel more optimistic about my spouse and marriage, but I am a better partner as I have learned endless understanding and compassion for people with depression. Please don’t ever stop making episodes!!

Nurselup · Oct 2021

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