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Business News · Harvey Castro MD, Junaid Kalia MD, & Edward Marx

Signal and Symptoms Podcast

by Harvey Castro MD, Junaid Kalia MD, & Edward Marx

Three healthcare AI experts who've watched millions wasted on failed projects. Dr. Harvey Castro, Dr. Junaid Kalia, Edward Marx, and guest experts cover all things healthcare AI - from digital transformation to clinical reality. Every Tuesday, we diagnose real failures, reveal what actually works, and help you avoid the expensive mistakes we've seen repeated everywhere. Because when AI decisions affect patient care, getting it right isn't optional.

Latest episodes

Showing 20 · updated from the feed

Will AI Replace the Doctor? The Empathy Debate, with Dr. Alan Weiss

“Medicine is fundamentally a relationship, and I don’t think AI replaces that.” That is where Dr. Alan Weiss plants his flag, seconds before Dr. Junaid Kalia throws down

Sep 9
9 min

Built Without Us: Physician Led AI Governance — Dr. Ryan Walsh (CMIO, Memorial Hermann)

Technology keeps getting built for clinicians and too often without them. This episode of Signal & Symptoms is about closing that gap. Dr. Junaid Kalia is joined by co-ho

Sep 1
10 min

The Decision, Not the Model: Lessons from Oncology AI — Dr. Agata Krasoń

“AI alone is very rarely the real breakthrough.” That’s how Dr. Agata Krasoń a Senior Clinical & Imaging Data Scientist at Roche, joining from Switzerland opens the conve

Aug 27
11 min

Run the Model Yourself: A Clinician’s Guide to Local AI

This one is a roundtable no guest, just the three of us. Dr. Junaid Kalia sits down with co-hosts Ed Marx and DR GPT™ Harvey Castro for a hands on, slightly geeky convers

Aug 19
10 min

Buyer to Builder — The Invisible Layer of Patient Monitoring

A small sensor sits on a tripod across the room — no wearable, no camera, nothing taped to a chest — and it’s reading a heartbeat through the air. What does it take for a

Aug 16
13 min

Explainable Clinical Digital Twins: One Engine for Power Plants and Patients

The same software engine can run a 400 megawatt power plant and simulate whether a cancer drug will survive a real world patient population. That’s not two companies it’s

Jul 23
17 min

Who Owns Your Medical Record Now? — Stephen Rouse, Co-Founder, Savva

For a generation, your medical record has lived behind the hospital’s firewall. What happens the day the patient walks in holding it already read, already interpreted by

Jul 9
17 min

Can Medicine Keep Up with AI? — Dr. Yeshe Kway (Oxford)

Somewhere in Oxford, there’s an AI that can produce a contrast-enhanced cardiac MRI without ever injecting the contrast. No needle, no gadolinium, no risk. It works and i

Jul 2
16 min

AI Won’t Replace Your Pediatrician — But It Will Change the Visit

The hardest part of a pediatric visit now happens before the appointment even begins. In this episode, Dr. Isha Mannering a board-certified pediatrician with 16 years in

Jun 23
18 min

How Brain Organoids Work (And Why They Could Replace Silicon)

The foundation of tomorrow's diagnostics is being rebuilt — and it starts in biology, not silicon. In this episode, Edmund White, biomedical innovator and bestselling au

Jun 9
18 min

Why AI Isn't the Tech Hype Hospital Leaders Think It Is

We built a healthcare system engineered for sick care, but the future of medicine belongs to those who seek health. In this episode, global Digital Health Futurist Phili

Jun 2
19 min

Healthcare AI: What To Know, What's Still Broken, and Where To Go Next

What does it actually cost when a diagnosis comes six months too late, a test gets ordered twice, or a treatment decision gets made without the best information available

May 26
13 min

What Hospitals Actually Need Before They'll Deploy Your AI

Will AI eliminate primary care — or finally give primary care physicians their time back? That's the central question driving this episode, as Dr. Junaid Kalia, Dr. Har

May 19
19 min

The Hidden Risk of AI-Powered Clinical Decisions

You already know not every AI tool belongs in your workflow. The real question is whether your filter is sharp enough to tell the difference. In this episode, Dr. Junaid

May 12
17 min

Why Will Digital Twins Change the Way We Treat Patients?

What if the most powerful diagnostic tool wasn't a scan or a lab result — but a continuously learning model of your patient, built from their own data? In this episode,

May 5
18 min

What Happens to Hospital Revenue When AI Replaces Primary Care?

Most healthcare conversations stop at disruption, but this one starts there. In this episode, three healthcare experts sit down to map what happens when AI doesn't just

Apr 28
17 min

The Business Playbook for Physicians Who Want to Win Beyond the Clinic

You went into medicine to save lives. But somewhere between residency and the real world, you started wondering — is there more I could be doing? That question is not a

Apr 21
19 min

How Ultrasound Frequencies Enable Early Intervention and Save Lives

What if the difference between a late diagnosis and a successful intervention was simply how we decode the signals of a sound wave? In this episode, we are discussing th

Apr 14
17 min

The Treatment Exists But Why Aren't Patients Getting It?

What if the real barrier to better patient outcomes isn't the medicine — it's the infrastructure to prescribe it well? This episode surfaces a broader signal: personaliz

Mar 31
20 min

AI Is In Healthcare—So Why Isn't It Working?

The overarching signal is: we're early, it's messy, and the people closest to the work know it best. In this episode, Dr. Andrew Kim joins hosts Dr. Junaid Kalia, Dr. Ha

Mar 24
20 min

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