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Technology · a16z

AI + a16z

by a16z

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

Latest episodes

Showing 20 · updated from the feed

How AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket

Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the biggest shift

Aug 7
23 min

Inside vLLM: The Engine Powering Open-Source AI

Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanced AI applica

Aug 6
46 min

Building Self-Accelerating AI with Mirendil

Matt Bornstein speaks with Mirendil cofounders Behnam Neyshabur and Harsh Mehta about their vision for building self-accelerating AI. After leading research efforts at G

Jun 24
40 min

Ideogram’s Open-Weights Image Model and the Future of AI Design

Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI a

Jun 15
42 min

Building Search for AI Agents with Exa CEO Will Bryk

Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era. The conversation covers Exa’s origins, why traditional search

Jun 4
49 min

AI Agents and the Fight for Customer Data

Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI. The conversation covers Fivetran’s merg

Jun 2
50 min

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI has rewrit

May 19
29 min

AI Infrastructure, Distribution, and the Next Wave of Software

Sophie Buonassisi speaks with Jennifer Li, general partner at a16z, about why infrastructure is becoming one of the most important areas in AI. They discuss how the shift

May 12
38 min

From Vector Databases to Knowledge Engines: The Next Layer of AI

Peter Levine speaks with Ash Ashutosh, CEO of Pinecone, about the launch of Nexus and the shift from vector databases to knowledge engines. As agents become the primary u

May 5
46 min

Why We Need Continual Learning

Elena Burger speaks with Malika Aubakirova, partner on the AI infrastructure team at a16z, about why today’s AI systems struggle to learn over time. They discuss the limi

Apr 28
18 min

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They d

Apr 21
59 min

Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinki

Apr 8
47 min

How AI Is Reshaping IT Services from the Inside

Joe Schmidt speaks with Peter Doyle, CEO of Treeline, about why the $100B managed service provider market is a decade behind modern technology and how Treeline is buildin

Apr 1
34 min

Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the

Mar 24
52 min

OpenClaw: Why the Internet Isn't Built for AI Agents

Yoko Li, Guido Appenzeller, and Joel de la Garza discuss OpenClaw, the open source personal AI assistant that's forcing a rethink of how identity, permissions, and securi

Mar 19
47 min

What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predicti

Mar 17
47 min

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Jack Neel speaks with Amjad Masad, CEO at Replit, about how AI is making it easier than ever to build and ship software without a technical background. They discuss Repli

Mar 10
1 h 39 min

Jack Altman & Martin Casado on the Future of VC

Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They cover a16

Mar 3
53 min

AI’s Capital Flywheel: Models, Money, and the Future of Power

a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the history of vent

Feb 24
57 min

Durable Execution and the Infrastructure Powering AI Agents

Raghu Raghuram, Managing Partner at a16z, and Sarah Wang, General Partner at a16z, speak with Samar Abbas, CEO of Temporal, about how durable execution became the infrast

Feb 19
1 h 03 min

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#31
all-time peak
83
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Where AI + a16z ranks today in each Apple Podcasts chart (US, Sep 16, 2026).

#102 ▲ 15 Technology US

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